MOCS3

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MOCS3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MOCS3, UBA4, molybdenum cofactor synthesis 3
External IDs MGI: 1916622 HomoloGene: 6108 GeneCards: MOCS3
RNA expression pattern
PBB GE MOCS3 206141 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014484

NM_001160330

RefSeq (protein)

NP_055299

NP_001153802.1
NP_001153802

Location (UCSC) Chr 20: 50.96 – 50.96 Mb Chr 2: 168.23 – 168.23 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Adenylyltransferase and sulfurtransferase MOCS3 is an enzyme that in humans is encoded by the MOCS3 gene.[3][4]

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. One of the enzymes required for the biosynthesis of MoCo is molybdopterin synthase (MPT synthase). The protein encoded by this gene adenylates and activates MPT synthase. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Matthies A, Nimtz M, Leimkuhler S (May 2005). "Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry". Biochemistry. 44 (21): 7912–20. doi:10.1021/bi0503448. PMID 15910006. 
  4. ^ a b "Entrez Gene: MOCS3 molybdenum cofactor synthesis 3". 

Further reading[edit]