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MPB can refer to:
- Maritime and Port Bureau, a bureau in Taiwan
- Media Prima Berhad, a Malaysian media corporation
- Música popular brasileira, Brazilian popular music
- Male pattern baldness
- Monthly Playboy, the Japanese edition of Playboy magazine
- Mountain pine beetle, a barkbeetle in the USA and Canada
- Mississippi Public Broadcasting, the public broadcasting network of Mississippi, United States
- Most Precious Blood (band), a New York City hardcore band
- Marginal private benefit, an economic term in externality theory
- Myelin basic protein, an antibody tested for implicated in Multiple sclerosis
- Morphotropic Phase Boundary, a zone e.g. found in PZT ceramics
- MPB4, a vocal and instrumental Brazilian group
| disambiguation page lists articles associated with the title MPB.
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