MPP2

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MPP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMPP2, DLG2, membrane palmitoylated protein 2
External IDsMGI: 1858257 HomoloGene: 3920 GeneCards: MPP2
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for MPP2
Genomic location for MPP2
Band17q21.31Start43,875,357 bp[1]
End43,909,711 bp[1]
RNA expression pattern
PBB GE MPP2 207984 s at fs.png

PBB GE MPP2 213270 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016695
NM_001356324

RefSeq (protein)

NP_057904
NP_001343253

Location (UCSC)Chr 17: 43.88 – 43.91 MbChr 11: 102.06 – 102.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

MAGUK p55 subfamily member 2 is a protein that in humans is encoded by the MPP2 gene.[5][6]

Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108852 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017314 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Mazoyer S, Gayther SA, Nagai MA, Smith SA, Dunning A, van Rensburg EJ, Albertsen H, White R, Ponder BA (Dec 1995). "A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A". Genomics. 28 (1): 25–31. doi:10.1006/geno.1995.1101. PMID 7590743. 
  6. ^ a b "Entrez Gene: MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)". 

Further reading[edit]