MRPL24

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MRPL24
PBB Protein MRPL11 image.jpg
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MRPL24, L24mt, MRP-L18, MRP-L24, mitochondrial ribosomal protein L24
External IDs MGI: 1914957 HomoloGene: 12241 GeneCards: MRPL24
RNA expression pattern
PBB GE MRPL24 218270 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024540
NM_145729

NM_026591

RefSeq (protein)

NP_078816
NP_663781

NP_080867.2
NP_080867

Location (UCSC) Chr 1: 156.74 – 156.74 Mb Chr 3: 87.92 – 87.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

39S ribosomal protein L24, mitochondrial is a protein that in humans is encoded by the MRPL24 gene.[3]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its Escherichia coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein.[3]

References[edit]

Further reading[edit]