Mitochondrial ribosomal protein L41

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Available structures
PDB Ortholog search: PDBe RCSB
Aliases MRPL41, BMRP, MRP-L27, MRPL27, RPML27, PIG3, Mitochondrial ribosomal protein L41
External IDs MGI: 1333816 HomoloGene: 13036 GeneCards: MRPL41
RNA expression pattern
PBB GE MRPL41 gnf1h09453 s at fs.png

PBB GE MRPL41 gnf1h09452 at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 9: 137.55 – 137.55 Mb Chr 2: 24.97 – 24.98 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.[3][4]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.[4]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (Sep 2001). "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders". Genomics. 77 (1-2): 65–70. doi:10.1006/geno.2001.6622. PMID 11543634. 
  4. ^ a b "Entrez Gene: MRPL41 mitochondrial ribosomal protein L41". 

Further reading[edit]