MRPS26

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MRPS26
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MRPS26, C20orf193, GI008, MRP-S13, MRP-S26, MRPS13, NY-BR-87, RPMS13, dJ534B8.3, mitochondrial ribosomal protein S26
External IDs MGI: 1333830 HomoloGene: 12778 GeneCards: MRPS26
RNA expression pattern
PBB GE MRPS26 gnf1h00455 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030811

NM_207207

RefSeq (protein)

NP_110438

NP_997090.1
NP_997090

Location (UCSC) Chr 20: 3.05 – 3.05 Mb Chr 2: 130.56 – 130.57 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.[3][4]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (Sep 2001). "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders". Genomics. 77 (1-2): 65–70. doi:10.1006/geno.2001.6622. PMID 11543634. 
  4. ^ a b "Entrez Gene: MRPS26 mitochondrial ribosomal protein S26". 

Further reading[edit]