MS4A3

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MS4A3
Identifiers
Aliases MS4A3, CD20L, HTM4, membrane spanning 4-domains A3
External IDs MGI: 2158468 HomoloGene: 4472 GeneCards: MS4A3
Genetically Related Diseases
Alzheimer's disease[1]
RNA expression pattern
PBB GE MS4A3 210254 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001031666
NM_001031809
NM_006138

NM_133246

RefSeq (protein)

NP_001026836
NP_001026979
NP_006129

NP_573509.1
NP_573509

Location (UCSC) Chr 11: 60.06 – 60.07 Mb Chr 19: 11.63 – 11.64 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Membrane-spanning 4-domains subfamily A member 3 is a protein that in humans is encoded by the MS4A3 gene.[4][5]

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.[5]

Interactions[edit]

MS4A3 has been shown to interact with CDKN3.[6]

References[edit]

Further reading[edit]