MTCH2

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MTCH2
Identifiers
Aliases MTCH2, MIMP, SLC25A50, HSPC032, mitochondrial carrier 2
External IDs MGI: 1929260 HomoloGene: 8645 GeneCards: MTCH2
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014342
NM_001317231
NM_001317232
NM_001317233

NM_019758
NM_001317241
NM_001317242
NM_001317243
NM_001317244

RefSeq (protein)

NP_001304160
NP_001304161
NP_001304162
NP_055157

Location (UCSC) Chr 11: 47.62 – 47.64 Mb Chr 2: 90.85 – 90.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene.[3][4][5][6]

Clinical significance[edit]

Variants of the MTCH2 gene may be associated with obesity.[7]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Grinberg M, Schwarz M, Zaltsman Y, Eini T, Niv H, Pietrokovski S, Gross A (June 2005). "Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha". Mol. Cell. Biol. 25 (11): 4579–90. doi:10.1128/MCB.25.11.4579-4590.2005. PMC 1140633Freely accessible. PMID 15899861. 
  4. ^ Gross A (June 2005). "Mitochondrial carrier homolog 2: a clue to cracking the BCL-2 family riddle?". J. Bioenerg. Biomembr. 37 (3): 113–9. doi:10.1007/s10863-005-6222-3. PMID 16167168. 
  5. ^ Schwarz M, Andrade-Navarro MA, Gross A (May 2007). "Mitochondrial carriers and pores: key regulators of the mitochondrial apoptotic program?". Apoptosis. 12 (5): 869–76. doi:10.1007/s10495-007-0748-2. PMID 17453157. 
  6. ^ Yu K, Ganesan K, Tan LK, Laban M, Wu J, Zhao XD, Li H, Leung CH, Zhu Y, Wei CL, Hooi SC, Miller L, Tan P (2008). Chang HY, ed. "A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers". PLoS Genet. 4 (7): e1000129. doi:10.1371/journal.pgen.1000129. PMC 2444049Freely accessible. PMID 18636107.  open access publication – free to read
  7. ^ Renström F, Payne F, Nordström A, et al. (April 2009). "Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden". Hum. Mol. Genet. 18 (8): 1489–96. doi:10.1093/hmg/ddp041. PMC 2664142Freely accessible. PMID 19164386. 

Further reading[edit]