MYL6

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MYL6
Identifiers
Aliases MYL6, ESMLC, LC17, LC17-GI, LC17-NM, LC17A, LC17B, MLC-3, MLC1SM, MLC3NM, MLC3SM, myosin light chain 6
External IDs MGI: 109318 HomoloGene: 69080 GeneCards: 4637
RNA expression pattern
PBB GE MYL6 212082 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_079425
NM_021019
NM_079423

NM_010860
NM_001317217
NM_001317218
NM_001317219
NM_001317220

RefSeq (protein)

NP_066299.2
NP_524147.2

NP_034990.1
NP_001304147.1

Location (UCSC) Chr 12: 56.16 – 56.16 Mb Chr 10: 128.49 – 128.49 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene.[1][2][3][4]

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.[4]

References[edit]

  1. ^ Bora PS, Bora NS, Wu X, Kaplan HJ, Lange LG (Jun 1994). "Molecular cloning, sequencing, and characterization of smooth muscle myosin alkali light chain from human eye cDNA: homology with myocardial fatty acid ethyl ester synthase-III cDNA". Genomics 19 (1): 186–8. doi:10.1006/geno.1994.1041. PMID 8188229. 
  2. ^ Hailstones DL, Gunning PW (Mar 1990). "Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function". Mol Cell Biol 10 (3): 1095–104. PMC 360973. PMID 2304459. 
  3. ^ Lenz S, Lohse P, Seidel U, Arnold HH (Jun 1989). "The alkali light chains of human smooth and nonmuscle myosins are encoded by a single gene. Tissue-specific expression by alternative splicing pathways". J Biol Chem 264 (15): 9009–15. PMID 2722814. 
  4. ^ a b "Entrez Gene: MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle". 

Further reading[edit]