MYO1C

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MYO1C
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MYO1C, MMI-beta, MMIb, NMI, myr2, myosin IC
External IDs MGI: 106612 HomoloGene: 32046 GeneCards: MYO1C
RNA expression pattern
PBB GE MYO1C 32811 at fs.png

PBB GE MYO1C 214656 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033375
NM_001080779
NM_001080950

NM_001080774
NM_001080775
NM_008659

RefSeq (protein)

NP_001074248
NP_001074419
NP_203693

Location (UCSC) Chr 17: 1.46 – 1.49 Mb Chr 11: 75.65 – 75.67 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Myosin-Ic is a protein that in humans is encoded by the MYO1C gene.[3][4]

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C (Apr 1997). "Cloning of the genes encoding two murine and human cochlear unconventional type I myosins". Genomics. 40 (2): 332–41. doi:10.1006/geno.1996.4526. PMID 9119401. 
  4. ^ a b "Entrez Gene: MYO1C myosin IC". 

Further reading[edit]