MYT1

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MYT1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MYT1, C20orf36, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A, ZC2H2C1, myelin transcription factor 1
External IDs MGI: 1100535 HomoloGene: 3332 GeneCards: MYT1
RNA expression pattern
PBB GE MYT1 210341 at fs.png

PBB GE MYT1 215822 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004535

NM_001171615
NM_001171616
NM_001171680
NM_008665

RefSeq (protein)

NP_004526

Location (UCSC) Chr 20: 64.15 – 64.24 Mb Chr 2: 181.76 – 181.83 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Myelin transcription factor 1 is a protein that in humans is encoded by the MYT1 gene.[3][4][5]

Function[edit]

The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.[5]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to visit related articles. [§ 1]

[[File:
MECP2_and_Associated_Rett_Syndrome_WP3584 Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to WikiPathways Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article
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MECP2_and_Associated_Rett_Syndrome_WP3584 Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to WikiPathways Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to miRBase Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to miRBase Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to Entrez Gene Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article Go to article
|{{{bSize}}}px|alt=MECP2 and associated Rett Syndrome edit]]
MECP2 and associated Rett Syndrome edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "WP3584". 

Interactions[edit]

MYT1 has been shown to interact with PIN1.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kim JG, Hudson LD (Dec 1992). "Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene". Molecular and Cellular Biology. 12 (12): 5632–9. doi:10.1128/mcb.12.12.5632. PMC 360502Freely accessible. PMID 1280325. 
  4. ^ Booher RN, Holman PS, Fattaey A (Aug 1997). "Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but not Cdk2 activity". The Journal of Biological Chemistry. 272 (35): 22300–6. doi:10.1074/jbc.272.35.22300. PMID 9268380. 
  5. ^ a b "Entrez Gene: MYT1 myelin transcription factor 1". 
  6. ^ Wells NJ, Watanabe N, Tokusumi T, Jiang W, Verdecia MA, Hunter T (Oct 1999). "The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression". Journal of Cell Science. 112 (19): 3361–71. PMID 10504341. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.