Petrov & Ruzic, 1983
The Macedonian mouse (Mus macedonicus) is a species of rodent in the family Muridae and order Rodentia. This rodent lives in the area from eastern Georgia and western Bulgaria to Israel. It is considered part of a Paleoarctic group along with three other types of rodents: M. musculus, M. spicilegus, and M. spretus.
The Mus macedonicus is a small rodent (15 g). It has very different fur color based upon location. In a study of numerous specimens in Turkey, the Mus macedonicus was found to have back colors ranging from dark brown to pale light brown to dark-reddish brown. There is a distinct line of demarcation along the flanks that separates top and bottom coloration. The bottom coloration ranged from whitish grey, pure white, yellowish white, and reddish white. The ears have tiny white hairs. This rodent has a tail that is dark brown on top and lighter on bottom.  The bottoms of the Mus macedonicus' feet are bare while the tops of their feet have white hairs. Mus macedonicus are nocturnal.
The sutura squamalis has distinction from other species because it is smoothed or protrudes slightly forward. The upper portion of the zygomatic arch is also more narrow than the lower portion. Mus macedonicus found in Israel are smaller than their Northern counterparts.
Body mass of Mus macedonicus exposed to short photoperiods increased - essentially they got bigger to stay warmer when it is cold. The short photoperiods also increased their resistance to cold while long photoperiods increased their ability to manage higher temperatures. Food consumption and waste production are lower in the mice that have longer photoperiods. These physiological changes allow Mus macedonicus to be well adapted to the changes that occur in the Mediterranean on a seasonal basis. This mouse also shows a genetic tendency for glial fibrilary acidic protein in their lens epithelial cells. This is a new marker of polymorphism in the Mus Genus.
- Kryštufek, B.; Vohralík, V. (2008). "Mus macedonicus". The IUCN Red List of Threatened Species. IUCN. 2008: e.T13966A4372730. doi:10.2305/IUCN.UK.2008.RLTS.T13966A4372730.en. Retrieved 7 August 2016.
- Orth, A. "Two Deeply Divergent Mitochondrial clades in the wild mouse Mus macedonicus reveal multiple glacial refuges south of Caucasus.". Heredity. 90: 353–357.
- Suzuki, Hitoshi. "Temporal, spatial, and ecological modes of evolution of Eurasian Mus based on mitochondrial and nuclear gene sequences". Molecular Phylogenetics and Evolution. 33: 626–646.
- Haim, A. (1999). "The thermoregulatory and metabolic responses to photoperiod manipulations of the Macedonian mouse (Mus macedonicus ), a post-fire invader.". Journal of Thermal Biology. 24: 279–286.
- Colat, Ercument. "The Morphological Analysis of Mus domesticus and Mus macedonicus (Mammalia: Rodentia) in Turkey". Tubitak. 30: 309–317.
- Boyer, Sylvie. "Recent evolutionary origin of the expression of the glial fibrillary acidic protein (GFAP) in lens epithelial cells. A molecular and genetic analysis of various mouse species". Molecular Brain Research. 10.
- Musser, G. G. and M. D. Carleton. 2005. Superfamily Muroidea. pp. 894–1531 in Mammal Species of the World a Taxonomic and Geographic Reference. D. E. Wilson and D. M. Reeder eds. Johns Hopkins University Press, Baltimore.
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