Both Machaon and Podalirius were highly valued surgeons and medics. In the Iliad he was wounded and put out of action by Paris. Machaon (or his brother) healed Philoctetes, Telephus and Menelaus, after he sustained an arrow at the hand of Pandarus, during the war. He was also supposed to possess herbs which were bestowed to his father Asclepius by Chiron, the centaur.
- The Latin name of a butterfly, the Old World Swallowtail (Papilio machaon), is derived from Machaon.
- Machaonia, a plant genus in Rubiaceae was named for Machaon.
- The Jovian trojan asteroid 3063 Makhaon is named after him.
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