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Madiha Iftikhar was born to Iftikhar Ahmed and Rehana Iftikhar, in Islamabad, Pakistan. Her parents used to do a show 'Boltey Haath' (speaking hands) which was based on sign language for deaf and mute special people. The show was aired on weekends on PTV in 1990s.
Madiha Iftikhar began her acting career, at the age of 17 years, in Partition Aik Safar, one of the most expensive dramas ever produced in Pakistan.
She is currently the Brand Ambassador for Olivia Whitening Creme and has appeared in its advertisement campaigns since February 2011.She also has appeared in:
- Kaise Yeh Junoon
- Dil Dard Dhuan
- Sarkar Sahab
- Pappu TV series
- Tujhe Pe Qurban
- Ishq Ki Inteha
- Mann Se Poocho
- Kitni girhen ab baaki hain
- Meri Behan Meri Dewrani
- Mujhe Apna Bana Lo
Iftikhar resides in Karachi. She is 5 ft 7 inches, being one of the tallest actresses and models in Pakistan.
She has publicly admitted that she is in a romantic relationship, in a Pakistani morning show in 2012 without mentioning any names or dropping any hints. However, in a Pakistani morning show aired on 31 March 2016 she was guest with her parents and sisters, she is married now, her husband does a Job in Dubai.