Magnesium glycinate

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Magnesium glycinate
IUPAC name
Magnesium diglycinate
Systematic IUPAC name
Magnesium bis(aminoacetate)
ECHA InfoCard 100.035.305 Edit this at Wikidata
Molar mass 172.423 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycine (one magnesium and two glycine molecules), and is sold as a dietary supplement.[1][2] It contains 14.1% elemental magnesium by mass. Accordingly, 141 mg of elemental magnesium is contained in 1000 mg of magnesium glycinate.

Magnesium glycinate is also often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate[3] form.


Magnesium glycinate has been studied with applicability to patients with a bowel resection[1] or pregnancy-induced leg cramps.[2] Less scientific research exists on magnesium glycinate in therapeutic applications than other more common forms of magnesium salt such as magnesium chloride, oxide or citrate. Magnesium glycinate has been considered in the context of magnesium’s potential influence on systems associated with the development of depression.[3]

See also[edit]


  1. ^ a b Schuette SA, Lashner BA, Janghorbani M (1994). "Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection". Journal of Parenteral and Enteral Nutrition. 18 (5): 430–5. doi:10.1177/0148607194018005430. PMID 7815675. Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.
  2. ^ a b Supakatisant C, Phupong V (2015). "Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial". Maternal & Child Nutrition. 11 (2): 139–45. doi:10.1111/j.1740-8709.2012.00440.x. PMC 6860204. PMID 22909270. Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.
  3. ^ a b "Magnesium Bisglycinate". 88Herbs.