Mamokgethi Phakeng at a photo shoot
1 November 1966|
Ga-Rankuwa, Pretoria, South Africa
|Occupation||Vice Chancellor University of Cape Town|
University of North-West|
University of the Witwatersrand
Rosina Mamokgethi Phakeng GCOB (née Mmutlana, born 1 November 1966) is a South African mathematician & researcher who is currently Vice-Chancellor at the University of Cape Town (UCT), as of 1 July 2018. Until her move to UCT in 2017, she was the Vice Principal, Research and Innovation, at the University of South Africa . She also acted as Executive Dean of the College of Science, Engineering and Technology  at UNISA. In 2002 she became the first black female South African to obtain a PhD in Mathematics Education. 
Mmutlana was born in Eastwood, Pretoria to Frank Mmutlana and Wendy Mmutlana (née Thipe). Her mother started as a domestic worker and factory worker who went back to school after giving birth to all her three children to complete Form 3 (Grade 9) which allowed her to study for her Primary Teachers Certificate and practice as a teacher. Her father, Frank Mmutlana, was one of the first black radio announcers at the South African Broadcasting Corporation (SABC).
She started school in 1972 at Ikageleng Primary in Marapyane village and Ikageng Primary in Ga-Rankuwa.She then attended the following schools; Tsela-tshweu higher primary; Tswelelang Higher Primary; Thuto-Thebe Middle School; Odi High School and Hebron.
She completed her matric with University Exemption in 1983(Grade 12) in the rural village of Hebron at the College of Education which also used to teach high school classes.
She achieved a BSc in Pure Mathematics at the University of North-West, and a MSc in Mathematics Education at the University of the Witwatersrand followed by a PhD in Mathematics Education at the same institution.
Throughout her life, Kgethi- as she is affectionately known- has won many awards for excellence in service. These honors include:
- The Order of the Baobab (Silver) for her excellent contribution in the field of science and representing South Africa on the international stage through her outstanding research work. The award was presented her by H.E Dr Jacob G Zuma, President of the Republic of South Africa. (April 2016)
- CEO Magazine award for being the most influential woman in education and training in South Africa (August 2013):
- NSTF award for being the most outstanding Senior Black Female Researcher over the last 5 to 10 years in recognition of her innovative, quality research on teaching
and learning mathematics in multilingual classrooms. (May 2011)
- Golden key International Society Honorary life membership (May 2009)
- Association of Mathematics Education of South Africa (AMESA) Honorary life membership (July 2009)
- Recognised as one of top three NRF Top Women in Research for 2006
- Amstel Salute to Success finalist (2005)
- Dr. T. W. Khambule Research Award for being the most outstanding young female black researcher for 2003: Conferred by the NSTF (May 2004)
- Outstanding Service Award (Education category). Conferred by the Sunday Sun and Christ Centred Church (2004).
- SA Woman of the Year (one of the three finalists) for the Science and Technology Category (2003).
- Prestige National Award South Africa’s Inspirational Women Achievers Award -Conferred by RCP Media, (June 2003).
- NRF Thuthuka Award (2003–2008).
- National Research Foundation/National Science Foundation USA/SA fellowship (2001; 2003)
- Mellon Award (1998 – 2000)
- SAB Women in Rural Areas Award (1997).
- Executive Dean of College of Science Engineering and Technology of University of South Africa
- Honorary Professor of University of the Witwatersrand
- Professor extraordinaire of Tshwane University of Technology
- Deputy Chairperson of National Committee for the International Mathematics Union 
- Trustee of FirstRand Limited Foundation 
- Trustee of Telkom SA Foundation 
- Board Member of South Africa, International Council for Science (ICSU) Board 
- Managing Director of Pythagoras
- Vice Chancellor of the University of Cape Town
She was married to Richard Setati for 19 years (1988–2007) and they had one son, Tsholofelo who was born in 1990. In 2012, she got married to Madimetja Lucky Phakeng, thereby adding the appendage "Phakeng" to her surname. Lucky Phakeng is an advocate currently heading the Takeover Regulation Panel. During the UCT Vice Chancellor selection process she apparently took anti-anxiety pills everyday which she now apparently carries around in her bag.
In 2004, Kgethi founded Adopt-A-Learner, a Non-profit Organisation with the aim of recognizing, promoting, and encouraging learner excellence in mathematics and science in black schools. According to her website, the purpose of the organization is to:
- To recognise, promote and encourage learner excellence in mathematics and science in black schools.
- To provide financial assistance to outstanding but financially underprivileged learners between Grades 7 and 12 by means of annual scholarships.
- To recruit individuals who are sympathetic to the aims and objectives of the project to support and mentor learners.
At the beginning of every year, her organization awards laptops at various schools to learners who perform well in mathematics and science.
Thusanani Foundation is a youth-led non-profit organisation that aims to bridge the educational information gap between rural high school learners and their urban counterparts through a multi-pronged holistic approach to learner development. Founded in 2011 by Morris Masutha and NtandoKabawo James, the Foundation was officially launched by the president of the Republic of South Africa, JacobZuma at the University of the Witwatersrand, on November 10, 2014. Kgethi, sits on the advisory board of the foundation.
In addition to the formal programmes she runs, Kgethi often uses her influence and social capital to empower and connect young people with their peers, or sponsors who can help them get ahead in life. Some of the young people who have benefited from her initiatives and mentoring include, among others Maanda Luxious Ndlovu and Madimetja "Brizo" Manyediwane
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- "Ass.Prof Mamokgethi Setati". University of the Witwatersrand. Wits Marketing. Archived from the original on 25 December 2012. Retrieved 30 August 2010.
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- "Profile of Trustees". FirstRand Foundation. Retrieved 1 September 2010.[permanent dead link]
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- Karolia, Sameerah (19 August 2010). "The problem solver". Mail & Guardian Online. Retrieved 1 September 2010.
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- Mnguni, Lukhona. "Did UCT kill Bongani Mayosi?". The M&G Online. Retrieved 2018-08-06.
| Vice-Chancellor of the University of Cape Town
July 2018 – present