Manabi Bandyopadhyay was born in Naihati, West Bengal in an educated family as Somnath Bandyopadhyay. She is the first transgender professor and first transgender person in India who has completed Doctor of Philosophy (PhD) in India. Bandyopadhyay was associate professor in Bengali at Vivekananda Satobarshiki Mahavidyalaya when she did her MPhil and she completes her Doctor of Philosophy in Jadavpur University in 2005 and gets convocation in 2006. She struggles a lot in her teaching profession and even she gets attacks and insults from the staffs when she was working in Vivekananda Satobarshiki Mahavidyalaya.So she then moved out of it and completed her Ph.d. She took charge as principal of Krishnagar Women's College on 7 June 2015 after a decade of struggle and she got this post purely based on her merit of experience for 16 years in profession and her degree of Ph.D. and this was possible after the order given by Mamata Banerjee. She is India's first openly transgender college principal, and began work as such in 2015 at the Krishnagar Women's College in Nadia district. Manabi is a devotee of Sarada Devi and she was initiated in spiritual life by Swami Atmasthananda. She wrote several works in Bengali literature. Her biography A Gift of Goddess Lakshmi speaks her journey from her childhood to her achievement of becoming India's first Third Gender Principal and it was done along with famous writer and journalist of Bengal, Jhimli Mukherjee Pandey. She runs India's first transgender Magazine, Abomanob which is now an annual magazine which runs for more than 20 years. In 2019 Bandyopadhyay played an important role in her debut film Purba Paschim Dakshin directed by Rajorshi Dey.
- "From Somnath to Manabi". The Indian EXPRESS. 2015-05-27.
- "India gets its first transgender college principal". indiatimes.com.
- India's first transgender college principal starts work
- "Rajorshi Dey's 'Purba Paschim Dakkhin' to hit the floors from tomorrow - Times of India". The Times of India. Retrieved 2019-09-11.