Manidipine

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Manidipine
Manidipine.svg
Clinical data
Trade namesManyper, etc.
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC35H38N4O6
Molar mass610.69 g/mol g·mol−1
3D model (JSmol)

Manidipine is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.[1][2][3][4][5]

It was patented in 1982 and approved for medical use in 1990.[6]

References[edit]

  1. ^ Cheer, S.M.; McClellan, K. (2001), "Manidipine: A Review of its Use in Hypertension", Drugs, 61 (12): 1777–99, doi:10.2165/00003495-200161120-00010, PMID 11693466, retrieved 2009-06-20[permanent dead link]
  2. ^ McKeage, K.; Scott, L.J. (2004), "Manidipine: A Review of its Use in the Management of Hypertension", Drugs, 64 (17): 1923–40, doi:10.2165/00003495-200464170-00011, PMID 15329044, retrieved 2009-06-20[permanent dead link]
  3. ^ Roca-cusachs, A.; Triposkiadis, F. (2005), "Antihypertensive Effect of Manidipine", Drugs, 65: 11–9, doi:10.2165/00003495-200565002-00003, PMID 16398058, retrieved 2009-06-20[permanent dead link]
  4. ^ Otero, M.L. (2007), "Manidipine–delapril combination in the management of hypertension", Vascular Health and Risk Management, 3 (3): 255–63, PMC 2293964, PMID 17703633
  5. ^ Mizuno, Kenji; Haga, Hiroshi; Takahashi, Michihiko; Fukuchi, Soitsu (August 1992), "Evaluation of manidipine hydrochloride, a new calcium antagonist, in the treatment of hypertensive patients with renal disorders", Current Therapeutic Research, 52 (2): 248–253, doi:10.1016/S0011-393X(05)80475-8, retrieved 2009-06-20[dead link]
  6. ^ Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 465. ISBN 9783527607495.