Mannatech headquarters in Coppell, Texas
|Traded as||NASDAQ: MTEX|
|Industry||Wellness, Personal care,
|Founded||Coppell, Texas, U.S. (November 1993 )|
|Founder||Samuel L. Caster|
|Headquarters||Coppell, Texas, U.S.|
|Alfredo Bala, CEO|
|Revenue||US$ 173.447 million (2013)|
|US$ -980 thousand (2013)|
|US$ -1.433 million (2013)|
|Total assets||US$ 47.560 million (2013)|
|Total equity||US$ 47.560 million (2013)|
Number of employees
|310 (Dec 2013)|
Mannatech, Incorporated, is a multinational multi-level marketing firm engaged in research, development, and distribution of "glyconutrients," the company's name for blends of plant-sourced saccharides. Mannatech was founded in November 1993 by Samuel L. Caster and is headquartered in Coppell, Texas. It operates in 24 countries, including the United States, Canada, Australia, countries in Asia, Africa, and within the EU.[a] The company's stock is traded on the NASDAQ exchange under the symbol MTEX. Mannatech employs 310 people and sells its products through approximately 229,000 active independent sales associates.
In 2006, Forbes magazine named Mannatech the #5 company on its annual list of the "200 Best Small Companies" and in 2007 Mannatech was ranked 12th in BusinessWeek magazine's 2007 list of America's "Top 100 Hot Growth Small Companies." The scientific validity of Mannatech’s key product Ambratose has been called into question by several researchers, and the company was the focus of a 2005 class action lawsuit (settled in 2008) for alleged violations of the Securities Exchange Act,  and a 2007 investigation (settled in 2009) by the Texas attorney general for alleged violations of that state's Deceptive Trade Practices Act.
- 1 Products
- 2 Scientific evaluation
- 3 Public scrutiny
- 4 Sam Caster
- 5 MannaRelief Ministries
- 6 See also
- 7 Citations and footnotes
- 8 External links
As of July 2011, the company offered 22 nutritional supplement products, two topical products, five skin care products, and four weight management/physical fitness products. Mannatech is most widely known for Ambrotose, its "glyconutritional" dietary supplement, which is a patented blend of plant-sourced saccharides used in its line of Ambrotose products. Glyconutritionals were formulated to support cellular communication by positively impacting human glycoforms, a claim that has generated controversy among some members of the scientific community. In an SEC filing, the company stated that its products "are formulated with predominately [sic] naturally-occurring, plant-derived, carbohydrate-based ingredients that are designed to use nutrients working through normal physiology to help achieve and maintain optimal health and wellness, rather than developing synthetic, carbohydrate-based products, as other companies are doing."
The opinion of independent glycobiologists is that the body cannot digest Ambrotose, as it lacks the enzymes needed. Prominent glycobiologist Ronald Schnaar, PhD of Johns Hopkins School of Medicine told 20/20 in a June 1, 2007 interview, "All of the sugar building blocks that we need in our body are made from the most common foods we eat."
Hudson Freeze, PhD, leading glycobiologist at the Sanford-Burnham Medical Research Institute said this about glyconutrients: "There are authentic, scientific studies that have looked at people drinking these kinds of materials, and it doesn't really do anything except increase flatulence." Freeze is a member of the editorial board of Glycobiology, and Schnaar serves as editor-in-chief. Schnaar and Freeze published a critique of Mannatech's products in Glycobiology in 2008, describing the lack of published clinical benefits of the "partially purified polydisperse plant polysaccharides" found in "Ambrotose Complex."
In Glycobiology, another article described the potential for the public to be misled about the science of glycobiology by the nebulous "glyconutrient" term. The authors' concern was that the public would be susceptible to the "scientific-sounding label" of glyconutrient, which may "generate a feeling of security and credibility...despite the lack of acceptance among many glycobiologists of the term." In November 2007, Science published an article in its "News Focus" section detailing the scientific controversy surrounding Mannatech. It included criticisms and comments from glycobiologists, including Ajit Varki, Raymond Dwek, Freeze, and Schnaar.
According to the Memorial Sloan–Kettering Cancer Center, Ambrotose has been "promoted aggressively to cancer patients" on the basis that it can help cellular health and boost the immune system, but that "strong scientific evidence to support these claims is lacking".
Mannatech has sponsored pre-clinical and clinical research on their products. The company states that these studies indicate that the products can be broken down into smaller, absorbable fragments by GI tract bacteria and can modify human serum glycosylation profiles. Additional studies sponsored by the company have indicated that the products also exert positive prebiotic effects  and induce positive effects on human brain wave activity, cognition, mood, and memory.
In a study published in the International Journal of Food Microbiology in 2010, Drs. Massimo Marzorati and Sam Possemiers (University of Ghent and ProDigest, Ghent, Belgium) and colleagues employed human gastrointestinal tract simulations and microbiological analysis to show that Ambrotose complex and Advanced Ambrotose powder exerted positive prebiotic effects. Both products exhibited quality selective fermentability throughout the entire colon with a positive and selective bifidus factor. They also demonstrated the possibility of enhancing species belonging to Bacteroidetes, a phylum recently associated with body weight management.
In a five-week combined Phase 1 and 2 open label, forced titration dose response study of 21 healthy adults, physicians and scientists from Southern Cross University showed that the Ambrotose AO dietary supplement was safe and raised serum Oxygen Radical Absorbance Capacity (ORAC) by 36.6%. The study was published in BMC Complementary and Alternative Medicine. In a subsequent 21-day randomized, double-blind, placebo-controlled crossover trial of 25 healthy adults, scientists from the University of Memphis showed that Ambrotose AO capsules significantly increased two measures of antioxidant capacity in the blood: ORAC and Trolox Equivalent Antioxidant Capacity (TEAC).
Two clinical trials (one conducted in the U.S. and one in Australia) investigated the effect of Ambrotose complex on brain function. Atiya N. Stancil and Leslie H. Hicks of Howard University conducted a randomized, double-blind, placebo-controlled study of Ambrotose in 62 healthy young adults. It was reported that a single one-tablespoon serving of Ambrotose complex significantly improved visual discrimination and working memory. A trial in 109 healthy middle-aged adults conducted by Talitha Best (a Mannatech-funded researcher) and colleagues showed that Ambrotose complex powder (4 grams/day for 12 weeks) significantly improved memory and psychological well-being.
Securities Exchange Act class-action lawsuit
The company has been known for its literature, websites, and multi-level marketing with claims of scientific links to cellular glycobiology long disputed by the relevant individual Nobel prize winners. On March 1, 2005 a jury trial was demanded and on September 9, 2005 a class-action lawsuit was filed against Mannatech for alleged violations of the Securities Exchange Act. The plaintiff class accused Mannatech of violating the act by "issuing a series of material misrepresentations"; specifically: failing to control its sales associates and allowing them to make false claims concerning the efficacy of Mannatech products. This caused a misleading price inflation of the company's stock. The plaintiffs consisted of the purchasers of Mannatech stock during the period August 10, 2004 through July 30, 2007. On March 20, 2008, Mannatech settled the class-action lawsuit by agreeing to pay $11.25 million to the plaintiff class. As part of the settlement, Mannatech admitted no wrongdoing.
Texas Attorney General civil complaint
Mannatech came under investigation by the Texas Attorney General on October 27, 2006 for alleged violations of that state's Deceptive Trade Practices Act. Samuel L. Caster, Mannatech's founder and chief executive officer at the time, stated: "We walk the fine line of always stating our case appropriately and always training our people: We're not into the treatment, cure or mitigation of disease. We're into the improvement of quality of life. Now, who can benefit from good nutrition? Sick people, well people, everybody. Everybody benefits from good nutrition."
On July 5, 2007, Texas Attorney General Greg Abbott formally charged Mannatech, MannaRelief, Sam Caster, and Reginald McDaniel, the company's medical director, with operating an illegal marketing scheme in violation of state law. A press release stated, "Today's enforcement action stems from a large-scale investigation by state authorities, who examined Mannatech's dubious claims about the health benefits of its products." In response to the civil complaint, Mannatech expanded its compliance department and began to provide periodic reports to the Attorney General's office to ensure that the marketing efforts of its affiliate network adhere to appropriate guidelines.
Mannatech settled the civil complaint on February 26, 2009 by agreeing to pay $4 million in restitution to clients who purchased products and $2 million to the state to cover its costs in the case. In addition, Sam Caster agreed to pay a $1 million civil penalty and steer clear of any type of leadership position or employment relationship with Mannatech for five years. When discussing the settlement at a news conference, Abbot stated, "Bottom line, this is a warning to the general public: Be wary of phony claims of magic cure-all pills or false hope in a bottle. You could be duped into purchasing something that has no real effect and no real value." Mannatech did not admit wrongdoing; settling was easier than debating Abbott, according to then-CEO Wayne Badovinus. "If they do it again, we will ensure they get put out of business," Abbott said.
One year later, Mannatech Co-CEO Robert Sinnott reflected on the ramifications of the legal action, saying, "The civil action related mainly to some actions by our salesforce. We were embarrassed and also financially impacted by the attorney general suit. We learned from that chapter and it is closed. We've reached a settlement and we've paid the fees associated with it. We've done everything in our power to correct that and make sure we're in compliance in the future."
A 20/20 undercover investigation that aired June 1, 2007 on ABC Television showed Mannatech's sales associates teaching sales recruits how to target Mannatech products to patients with specific illnesses in a manner that purportedly does not violate U.S. federal law, including U.S. Food and Drug Administration regulations, by avoiding direct claims that the products cure any particular diseases. Mannatech CEO Sam Caster was interviewed for the show and told 20/20 that Mannatech makes no specific health claims about its products. "I don't think dietary supplements treat, cure, mitigate anything. It is not meant to substitute a doctor's oversight, but it plays an important role in the whole health equation."
Mannatech announced in August 2007 that company founder Sam Caster was stepping down as CEO of Mannatech, to be replaced by Wayne Badovinus as the new chief executive. Several corporate initiates were undertaken, but after 17 months on the job Badovinus resigned in December 2009.
Another member of the board resigned shortly after. Mannatech's Chief Science Officer Robert Sinnott and Mannatech's Chief Financial Officer Steve Fenstermacher were named Co-CEOs. Fenstermacher later resigned.
Publicity over the company's lawsuits began to damage the balance sheets and stock performance. After profits of $32 million in 2006 and $6.6 million in 2007, Mannatech reported a $12.6 million loss in 2008 and a $17.3 million loss in 2009. By mid-year 2010, one quarter of Mannatech's sales were gone. 2010 losses were $10.6 million. As the company's market capitalizations continued to fall, S&P Indices dropped it from the S&P 600 Index, stating "They are no longer representative of the small cap market space." Recruiting efforts continued dropping in 2011, widening company losses to 20.6 million.
Ben Carson endorsement
From 2004 until early 2014, neurosurgeon and conservative speaker Ben Carson made videos and spoke at company events promoting Mannatech and endorsing Mannatech's products. Carson's endorsement of the company was the subject of an article in National Review, which described the connection as being in poor judgement and damaging to Carson's speculative 2016 presidential run. When confronted with this, Carson distanced himself from the company and stated that his connection with Mannatech was strictly as a paid speaker and that he was unaware of the company's legal history.
Prior to Mannatech
Samuel L. Caster is the founder and former Chairman of the Board of Directors of Mannatech. His first major business venture, Eagle Shield, was an insulation product that claimed to utilize new technology developed by NASA and could reduce heating and cooling costs by up to 40%. In May 1988, the Attorney General of Texas concluded that the product's technology long predated NASA and did not reduce consumers' bills in the amounts advertised. Caster agreed to cease the misleading claims made about Eagle Shield. Caster's second product, the "Electrocat," was sold as a pest control device. The Electrocat reportedly emitted pulsed vibrations that repelled rats, crickets, snakes, ticks, spiders, mosquitoes, and scorpions. However, in January 1991, the Attorney General of Texas investigated the product and found that the Electrocat emitted no vibrations whatsoever. The Attorney General declared, "The device is a hoax, and stands on the same scientific footing as a perpetual motion machine." Caster was ordered to stop selling the Electrocat and to reimburse the state $125,000 in investigative costs.
Caster then started Mannatech in 1994, coinciding with Congress' passage of the Dietary Supplement Health and Education Act of 1994, which made profitable marketing of a wider spectrum of dietary supplements a possibility.
Consultant to Mannatech
On August 22, 2007, Sam Caster resigned as CEO of Mannatech. On October 19, 2007, it was reported that the company had fired Grant Thornton LLP as its auditor after the accounting firm demanded that Mannatech remove Sam Caster from all responsibilities. Sam Caster was barred by the attorney general of Texas from serving as a director, officer, or employee of Mannatech for five years—from February 2009 until February 2014. Caster was also barred from taking a role in any other multi-level marketing programs during that time. Despite this, then-CEO Wayne Badovinus stated Caster would work as a consultant answering directly to him. The attorney general’s office agreed Caster could serve as an outside consultant to the company.
In March 2014, Caster appeared as main speaker at a Mannatech videoconference event with sales associates for the company's new skin rejuvenation product. Introduced as the company’s founder and "visionary," he explained the company’s new product and his role in its creation. "Oh my gosh, This stuff really works." he said, of the product. "No one could have predicted it would have that immediate an impact."
MannaRelief Ministries is a 501(c)(3) non-profit organization founded in 1999 by Sam Caster. William A. Mullens, Mr. Caster’s brother-in-law, serves as MannaRelief’s Executive Director, and Caster’s wife, Linda, serves as Chairman of the Board. MannaRelief receives a portion of the proceeds from Mannatech products purchased on "automatic order", and in turn distributes PhytoBlend powder (a dietary supplement purchased at cost from Mannatech) to various unidentified orphanages and international relief organizations. From 2009 to 2011, Manntech provided a total of $1.5 million in cash donations to MannaRelief, and MannaRelief purchased $1.6 million worth of products from Mannatech.
Citations and footnotes
- Mannatech operates in the United States, Canada, Australia, the United Kingdom, Japan, New Zealand, Republic of Korea, Taiwan, Denmark, Germany, Mexico, South Africa, Namibia, Singapore, Sweden, Norway, Austria, the Netherlands, Ireland, Estonia, Finland, the Czech Republic, Hong Kong, and Ukraine.
- "Mannatech / United States Securities and Exchange Commission Form 10-K". United States Securities and Exchange Commission. Retrieved April 29, 2013.
- "Glyconutrients". Memorial Sloan-Kettering Cancer Center. October 11, 2012. Retrieved August 31, 2013.
- "Mannatech, Inc.". Mannatech, Inc. Retrieved July 8, 2007.
- "Mannatech Announces Official Opening in Ukraine; becomes company's 24th global market". MarketWatch. July 8, 2013. Retrieved March 31, 2015.
- "The 200 Best Small Companies". Forbes. October 12, 2006. Retrieved November 18, 2009.
- "Hot Growth Companies: The Fastest-Growing Companies of 2007". Bloomberg BusinessWeek. May 2007. Retrieved November 21, 2009.
- Sataline, Suzanne (May 11, 2007). "Health Claims by Sales Force Boost Supplement Firm; Mannatech's Products Attract the Gravely Ill; Disclaimers on Labels". The Wall Street Journal. Retrieved July 8, 2007.
Some researchers say they doubt that Ambrotose offers any health benefits. Hudson Freeze, who studies complex carbohydrates as a professor of glycobiology at the Burnham Institute for Medical Research in La Jolla, Calif., contends the body can't digest Ambrotose because humans lack the enzymes necessary to break down the plant fibers it contains into simple sugars.(subscription required)
- Avila, Jim; Geoff Martz; Andrew Paparella (June 1, 2007). "Cure for Your Disease or Empty Promise?". ABCNews Internet Ventures. Retrieved July 8, 2007.
- Schnaar RL, Freeze HH (2008). "A 'Glyconutrient Sham'" (PDF). Glycobiology 18 (9): 652–657. doi:10.1093/glycob/cwm098. PMID 17855741.
- Torok CB, Murray TH (2008). "Wielding the sword of professional ethics against misleading dietary supplement claims". Glycobiology 18 (9): 660–663. doi:10.1093/glycob/cwn060.
- Jocelyn Kaiser (2007). "Who Owns Glycobiology?". Science 318 (5851): 734–737. doi:10.1126/science.318.5851.734. PMID 17975043.
- "Milberg Weiss Announces the Filing of a Class Action Lawsuit Against Mannatech, Inc.". All Business. September 12, 2005. Retrieved May 27, 2009.
- "Texas Attorney General Charges Mannatech with Unlawful, Misleading Sales Practices". Texas Attorney General Greg Abbott. July 5, 2007. Retrieved July 8, 2007.
- Mannatech, Incorporated (March 16, 2006). "Form Mannatech, Incorporated: 10K SEC Public Filing for FY 2005". United States Securities and Exchange Commission. Retrieved May 23, 2010.
- "Ronald L. Schnaar, PhD". Johns Hopkins University. Retrieved May 21, 2010.
- "Hudson Freeze, PhD". Sanford-Burnham Medical Research Institute. Retrieved May 21, 2010.
- "Editorial Board". Glycobiology. Retrieved May 21, 2010.
- "Glyconutrients". Memorial Sloan–Kettering Cancer Center. October 11, 2012. Retrieved August 2013.
- "Publications". Mannatech, Inc. Retrieved March 18, 2012.
(Article acknowledges studies that received at least partial funding)
- Sinnott, RA; Ramberg J; Kirchner JM; et al. (2007). "Utilization of arabinogalactan, aloe vera gel polysaccharides, and a mixed saccharide dietary supplement by human colonic bacteria in vitro". Int J Probiotics Prebiotics 2: 97–104.
- Alavi, A; Fraser O; Tarelli E; Bland M; Axford J (2011). "An open-label dosing study to evaluate the safety and effects of a dietary plant-derived polysaccharide supplement on the N-glycosylation status of serum glycoproteins in healthy subjects". Eur J Clin Nutr 65 (5): 648–656. doi:10.1038/ejcn.2010.263. PMC 3087895. PMID 21224866.
- Marzorati, M; Verhelst A; Luta G; et al. (2010). "In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements". Int J Food Microbiology 139 (3): 168–76. doi:10.1016/j.ijfoodmicro.2010.02.030. PMID 20362351. Retrieved July 19, 2011.
- Wang, C; Szabo JS; Dykman RA (2004). "Effects of a carbohydrate supplement on resting brain activity". Integrative Physiol & Behavioral Sci 39 (2): 126–138. doi:10.1007/BF02734278.
- Stancil AN, Hicks LH (2009). "Glyconutrients and perception, cognition, and memory". Percep Motor Skills 108 (1): 259–270. doi:10.2466/PMS.108.1.259-270. PMID 19425467.
- Best, T; Kemps E. Bryan J (2010). "Saccharide effects on cognition and well-being in middle-aged adults: A randomized controlled trial". Developmental Neuropsych 35 (1): 66–80. doi:10.1080/87565640903325709.
- Bloomer, RJ; Canale RE; Blankenship MM; Fisher-Wellman KH (2010). "Effect of Ambrotose AO on resting and exercise-induced antioxidant capacity and oxidative stress in healthy adults". NutrJ 9 (49): 1–17.
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- "Coppell-Based Mannatech to Pay Millions to Settle Diet-Supplement Lawsuit". Ft. Worth Star Telegram. February 26, 2009. Retrieved February 26, 2009.
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- Sataline S (August 22, 2007). "Caster Resigns as CEO of Mannatech". The Wall Street Journal. Retrieved April 6, 2008.
- Roberson, Jason (December 4, 2009). "Mannatech CEO quits after 17 months on the job". Dallas Morning News. Retrieved December 27, 2009.
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