The Manning criteria are a diagnostic algorithm used in the diagnosis of irritable bowel syndrome (IBS). The criteria consist of a list of questions the physician can ask the patient. The answers are used in a process to produce a diagnostic decision regarding whether the patient can be considered to have IBS.
The Manning criteria have been compared with other diagnostic algorithms for IBS, such as the Rome I criteria, the Rome II process, and the Kruis criteria. A 2013 valiadation study found the Manning criteria to have less sensitivity but more specificity than the Rome criteria.
The Manning criteria are:
- Onset of pain linked to more frequent bowel movements
- Looser stools associated with onset of pain
- Pain relieved by passage of stool
- Noticeable abdominal bloating
- Sensation of incomplete evacuation more than 25% of the time
- Diarrhea with mucus more than 25% of the time
- Manning AP, Thompson WG, Heaton KW, Morris AF (1978). "Towards positive diagnosis of the irritable bowel.". Br Med J 2 (6138): 653–4. doi:10.1136/bmj.2.6138.653. PMC 1607467. PMID 698649.
- Fass R, Longstreth GF, Pimentel M et al. (2001). "Evidence- and consensus-based practice guidelines for the diagnosis of irritable bowel syndrome". Arch. Intern. Med. 161 (17): 2081–8. doi:10.1001/archinte.161.17.2081. PMID 11570936.
- "Validation of the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care.". Gastroenterology. 145: 1262–70.e1. Dec 2013. doi:10.1053/j.gastro.2013.08.048. PMID 23994201.