Manning criteria

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The Manning criteria are a diagnostic algorithm used in the diagnosis of irritable bowel syndrome (IBS). The criteria consist of a list of questions the physician can ask the patient.[1] The answers are used in a process to produce a diagnostic decision regarding whether the patient can be considered to have IBS.

The Manning criteria have been compared with other diagnostic algorithms for IBS, such as the Rome I criteria, the Rome II process, and the Kruis criteria.[2] A 2013 valiadation study found the Manning criteria to have less sensitivity but more specificity than the Rome criteria.[3]

The Manning criteria are: At least 2 of the following:

  1. Onset of pain linked to more frequent bowel movements
  2. Looser stools associated with onset of pain
  3. Pain relieved by passage of stool
  4. Noticeable abdominal bloating
  5. Sensation of incomplete evacuation more than 25% of the time
  6. Diarrhea with mucus more than 25% of the time


  1. ^ Manning AP, Thompson WG, Heaton KW, Morris AF (1978). "Towards positive diagnosis of the irritable bowel.". Br Med J. 2 (6138): 653–4. doi:10.1136/bmj.2.6138.653. PMC 1607467Freely accessible. PMID 698649. 
  2. ^ Fass R, Longstreth GF, Pimentel M, et al. (2001). "Evidence- and consensus-based practice guidelines for the diagnosis of irritable bowel syndrome". Arch. Intern. Med. 161 (17): 2081–8. doi:10.1001/archinte.161.17.2081. PMID 11570936. 
  3. ^ "Validation of the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care.". Gastroenterology. 145: 1262–70.e1. Dec 2013. doi:10.1053/j.gastro.2013.08.048. PMID 23994201.