Marcus Raichle

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Marc Raichle

Marcus E. Raichle is an American neurologist at the Washington University School of Medicine in Saint Louis, Missouri. He is a professor in the Department of Radiology with joint appointments in Neurology, Neurobiology and Biomedical Engineering. His research over the past 40 years has focused on the nature of functional brain imaging signals arising from PET and fMRI and the application of these techniques to the study of the human brain in health and disease.[1]


Noteworthy accomplishments during this time have been the discovery of the relative independence of blood flow and oxygen consumption during changes in brain activity which provided the physiological basis of fMRI;[2] the discovery of a default mode of brain function (i.e., organized intrinsic activity) and its signature system, the brain’s default mode network;[3] and, the discovery that aerobic glycolysis contributes to brain function independent of oxidative phosphorylation.[4][5]


  • Raichle, ME (2010). "The brain's dark energy". Scientific American 302 (3): 28–33. PMID 20184182. 


Professional memberships[edit]

  • Member: National Academy of Sciences, Institute of Medicine, American Academy of Arts and Sciences.
  • Fellow: American Association Advancement of Science.

Professional societies[edit]

  • Society for Neuroscience
  • American Neurological Association
  • American Academy Neurology
  • International Society Cerebral Blood Flow & Metabolism.


In 2001, he was a co-recipient, with Michael Posner and Steven Peterson, of the University of Louisville Grawemeyer Award in Psychology.[6] In 2010, he was awarded the Ariëns Kappers Medal from the Royal Netherlands Academy of Arts and Sciences. In 2014, he was a co-recipient of the Kavli Prize awarded by the Norwegian Academy of Science and Letters with Brenda Milner of the Montreal Neurological Institute at McGill University and John O’Keefe of University College London.[7]


  1. ^ "Academy Members". 
  2. ^ Petersen, SE; Fox PT, Posner MI, Mintun M, Raichle ME (1988). "Positron emission tomographic studies of the cortical anatomy of single-word processing". Nature 331 (6157): 585–589. doi:10.1038/331585a0. PMID 3277066. 
  3. ^ Fox, MD; Zhang D, Snyder DZ, Raichle ME (2009). "The global signal and observed anticorrelated resting state brain networks". J. Neurophysiology 101 (6): 3270–3283. doi:10.1152/jn.90777.2008. PMC 2694109. PMID 19339462. 
  4. ^ Vaishnavi, SN; Vlassenko AG, Rundle MM, Snyder AZ, Mintun MA, Raichle ME (2010). "Regional aerobic glycolysis in the human brain". PNAS 107 (41): 17757–17762. doi:10.1073/pnas.1010459107. PMC 2955101. PMID 20837536. 
  5. ^ Vlassenko, AG; Vaishnavi SN, Couture L, Sacco D, Shannon BJ, Mac, RH, Morris JC, Raichle ME, Mintun MA (2010). "Spatial correlation between brain aerobic glycolysis and amyloid-β deposition". PNAS 107 (41): 17763–17767. doi:10.1073/pnas.1010461107. PMC 2955133. PMID 20837517. 
  6. ^ "2001- Michael Posner, Marcus Raichle and Steven Peterson". 
  7. ^ "Nine Scientists Share Three Kavli Prizes". 

External links[edit]