Margaret Collins-O'Driscoll (1878 – 17 June 1945) was an Irish Cumann na nGaedheal politician. She was the sister of the Irish revolutionary leader Michael Collins. She was educated at Baggot Street Training College and was a schoolteacher and school principal before entering politics.
She was first elected to Dáil Éireann as a Cumann na nGaedheal Teachta Dála (TD) for the Dublin North constituency at the 1923 general election. She was re-elected at every subsequent election until she lost her seat at the 1933 general election. Her great-granddaughter is the actress Dervla Kirwan. 
- "Margaret Collins-O'Driscoll". Centre for Advancement of Women in Politics (QUB). Retrieved 22 September 2008.
- "Ms. Margaret Collins-O'Driscoll". Oireachtas Members Database. Retrieved 27 April 2009.
- "Margaret Collins-O'Driscoll". ElectionsIreland.org. Retrieved 27 April 2009.
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