Marion Koopmans

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Marion Koopmans
Marion Koopmans 2018.jpg
Koopmans in 2018
Born (1956-09-21) 21 September 1956 (age 64)
Alma materUtrecht University
Scientific career
InstitutionsNational Institute for Public Health and the Environment
Erasmus MC
ThesisDiagnosis and epidemiology of torovirus infections in cattle (1990)

Maria Petronella Gerarda Koopmans[1] (born 21 September 1956) is a Dutch virologist who is Head of the Erasmus MC Department of Viroscience. Her research considers emerging infectious diseases, noroviruses and veterinary medicine. In 2018 she was awarded the Netherlands Organisation for Scientific Research (NWO) Stevin Prize. She serves on the scientific advisory group of the World Health Organization.

Early life and education[edit]

Koopmans studied veterinary medicine at Utrecht University.[2] She graduated from her Master's degree 1976, and remained there for her doctoral research. She earned two graduate degrees in veterinary medicine, and was officially registered as a veterinary microbiologist in 1977. She became increasingly interested in virology, and moved to the United States to specialise in viruses that can be transmitted between animals and humans.[3] From 1991 to 1994 Koopmans completed a fellowship at the Centers for Disease Control and Prevention, where she studied enteric viruses.[2] She joined the Virology Division, where she focussed on torovirus in cattle.

Research and career[edit]

Koopmans joined the National Institute for Public Health and the Environment (RIVM), where she was appointed Chief of Virology. She was involved with restructuring the department, and translating their research out of the laboratory and into practical applications for the control of infectious diseases. In 2006 she was appointed as Professor of Public Health at the Erasmus MC hospital in Rotterdam, which allowed her to strengthen the evidence-base of infectious disease research. Her laboratory makes use of basic scientific studies and epidemiology to understand the pathogenesis of infectious diseases, to establish their transmission routes and to translate this research base into diagnostic tools.

In 2003, when Influenza A virus subtype H7N7 spread around the Netherlands, Koopmans experienced her first infectious diseases outbreak. She was involved with the development of a coordinated public response, working with veterinarians and physicians to quickly develop public health policy. Her experiences in leading the response to the avian influenza outbreak prepared her for subsequent epidemics, including Middle East respiratory syndrome (MERS) and Zika virus. She was on the team that found, in 2013, that dromedary camels were an intermediate host for the virus that causes MERS.[4] She has since worked with Elmoubasher Farag to test camels for antibodies against MERS.[5]

During the Ebola outbreak in West Africa, Koopmans was responsible for the deployment of mobile laboratories in Sierra Leone and Liberia. Her Erasmus MC team trained volunteers to run testing and treatment programmes.[6] Koopmans is a member of the scientific advisory group (SAG) of the World Health Organization's R&D Blueprint project.[7] The project looks to understand what has gone wrong with epidemic and pandemic responses, and looks to build global disease preparedness.[7] As part of this effort, Koopmans analysed the public health response to the Zika virus. She identified three significant bottlenecks to an efficient response; including delays in regulatory approvals, challenges in the logistics of laboratory support and the absence of a structured timeline for funding.[8] Koopmans also leads the World Health Organization centre for Emerging Viral Diseases.[9] She is the scientific coordinator of COMPARE, a Horizon 2020 project that looks to develop next generation sequencing techniques for outbreak identification and mapping.[10] COMPARE look to contain and mitigate foodborne illnesses.[10]

In 2018 Koopmans was honoured by the Netherlands Organisation for Scientific Research (NWO) for her work on the transfer of viruses from animals to humans.[11] In 2019 she was awarded a $9 million NWO grant to establish a consortium, the Versatile Emerging infectious disease Observatory (VEO), that will study how changes in environment and travel will impact the risk of infectious diseases.[12][13] The diseases considered by VEO include vector-borne and zoonotic diseases, as well as hidden pathogens.[14] Koopmans wrote an article for Nature in which she called for a transformation in epidemic preparedness and response.[15] In the article, she quoted the World Health Organization's leader on health emergencies, “We are entering a very new phase of high-impact epidemics… This is a new normal,”.[16] In 2019 Koopmans was elected member of the Royal Netherlands Academy of Arts and Sciences.[17]

From the start of 2020, Koopmans worked to understand SARS-CoV-2 and the spread of coronavirus disease.[3][18][19] In the Netherlands, Koopmans made an effort to test healthcare workers, and identified that there were large numbers of asymptomatic carriers amongst the dutch population.[20] With her team at the Erasmus MC, Koopmans looked to understand the efficacy of antibody tests.[21][22] Alongside leading the scientific response, Koopmans was also involved with scientific communication about the virus, making use of social media and media interviews to share up-to-date research with the public.[23][24] Koopmans said that as humans occupied more of planet earth, the number of dangerous diseases transmitted from animals to humans would increase.[25] She was appointed to the coronavirus disease advisory panel of the European Commission.[25] The panel served to develop public health recommendations to the member states during the pandemic.[25]

On 02 December 2020, Koopmans was appointed to the 13 member team of the World Health Organization's investigation into the origins of COVID-19.[26]

Awards and honours[edit]

Selected publications[edit]

  • Fouchier, R.A.M. (Ron) Schneeberger, P.M. (Peter) Rozendaal, F.W. (Frans) Broekman, J.M. (Jan) Kemink, S.A. (Stiena) Munster, V.J. (Vincent) Rimmelzwaan, G.F. (Guus) Schutten, M. (Martin) Doornum, G.J.J. (Gerard) van Koch, G. (Guus) Bosman, A. (Arnold) Koopmans D.V.M., M.P.G. (Marion) Osterhaus, A.D.M.E. (Albert) Kuiken, T. (Thijs) (3 February 2004). "Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome". Proceedings of the National Academy of Sciences of the United States of America. 101 (5): 1356–61. doi:10.1073/pnas.0308352100. OCLC 929966166. PMC 337057. PMID 14745020.CS1 maint: multiple names: authors list (link)
  • Newell, Diane G.; Koopmans, Marion; Verhoef, Linda; Duizer, Erwin; Aidara-Kane, Awa; Sprong, Hein; Opsteegh, Marieke; Langelaar, Merel; Threfall, John; Scheutz, Flemming; der Giessen, Joke van (30 May 2010). "Food-borne diseases — The challenges of 20years ago still persist while new ones continue to emerge". International Journal of Food Microbiology. Future Challenges to Microbial Food Safety. 139: S3–S15. doi:10.1016/j.ijfoodmicro.2010.01.021. ISSN 0168-1605. PMC 7132498. PMID 20153070.
  • Koopmans, Marion; Duizer, Erwin (1 January 2004). "Foodborne viruses: an emerging problem". International Journal of Food Microbiology. 90 (1): 23–41. doi:10.1016/s0168-1605(03)00169-7. ISSN 0168-1605. PMC 7127053. PMID 14672828.
  • "The Novel Coronavirus Outbreak: What We Know and What We Don't". Cell. 180 (6): 1034–1036. 19 March 2020. doi:10.1016/j.cell.2020.02.027. ISSN 0092-8674. PMC 7154513. PMID 32078801.

References[edit]

  1. ^ Her complete name is given in this library link (PhD thesis)
  2. ^ a b "External Scientific Advisory Council". KWR. Retrieved 19 May 2020.
  3. ^ a b "Koopmans". Studium Generale Universiteit Utrecht (in Dutch). 22 December 2015. Retrieved 18 May 2020.
  4. ^ Smriti Mallapaty (December 2, 2020), Meet the scientists investigating the origins of the COVID pandemic Nature.
  5. ^ Smriti Mallapaty (December 2, 2020), Meet the scientists investigating the origins of the COVID pandemic Nature.
  6. ^ "Blue Print SAG members" (PDF). Retrieved 19 May 2020.
  7. ^ a b "WHO | Marion Koopmans: greater regional capacity to fight disease outbreaks". WHO. Retrieved 18 May 2020.
  8. ^ Koopmans, Marion; de Lamballerie, Xavier; Jaenisch, Thomas; Rosenberger, Kerstin D; Morales, Ivonne; Marques, Ernesto T A; Viana, Isabelle F T; Brasil, Patricia; Rabello, Renata; Avelino-Silva, Vivian I; Segurado, Aluisio (1 February 2019). "Familiar barriers still unresolved—a perspective on the Zika virus outbreak research response". The Lancet Infectious Diseases. 19 (2): e59–e62. doi:10.1016/S1473-3099(18)30497-3. ISSN 1473-3099. PMID 30420230.
  9. ^ "EMERGE - EMERGE: Efficient response to highly dangerous and emerging pathogens at EU level". www.emerge.rki.eu. Retrieved 19 May 2020.
  10. ^ a b "Contacts - Compare Europe". www.compare-europe.eu. Retrieved 18 May 2020.
  11. ^ a b "Stevin Prize for prof. dr. Marion Koopmans | Erasmus University Rotterdam". www.eur.nl. Retrieved 18 May 2020.
  12. ^ "Over 9 million for four research projects from Utrecht with new type of funding | News | Universiteit Utrecht". www.uu.nl. Retrieved 18 May 2020.
  13. ^ "Versatile Emerging infectious disease Observatory". Cordis. Retrieved 18 May 2020.
  14. ^ "Q&A: We have to rethink disease detection to get ahead of the outbreak after coronavirus". Horizon: the EU Research & Innovation magazine. Retrieved 18 May 2020.
  15. ^ "Nature publishes article by key GloPID-R participants calling for new approach to future epidemic preparedness and response – GloPID-R". www.glopid-r.org. Retrieved 19 May 2020.
  16. ^ Bedford, Juliet; Farrar, Jeremy; Ihekweazu, Chikwe; Kang, Gagandeep; Koopmans, Marion; Nkengasong, John (2019). "A new twenty-first century science for effective epidemic response". Nature. 575 (7781): 130–136. doi:10.1038/s41586-019-1717-y. ISSN 1476-4687. PMC 7095334. PMID 31695207.
  17. ^ "Marion Koopmans". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 18 November 2019.
  18. ^ MC, Erasmus (28 February 2020). "Marion Koopmans: coronavirus is not so contagious at all". www.erasmusmc.nl (in Dutch). Retrieved 18 May 2020.
  19. ^ MC, Erasmus (28 February 2020). "Q & A about coronavirus with Marion Koopmans". www.erasmusmc.nl (in Dutch). Retrieved 18 May 2020.
  20. ^ "'Silent Spreaders' Speed Coronavirus Transmission". NPR.org. Retrieved 18 May 2020.
  21. ^ "Erasmus University researcher discusses about the accuracy of test kits". Science|Business. Retrieved 18 May 2020.
  22. ^ Cox, David (10 May 2020). "Can antibody testing deliver on promises to lift the lockdown?". The Observer. ISSN 0029-7712. Retrieved 18 May 2020.
  23. ^ Lauerman, John. "Stay Home During the 'Crisis of Our Generation': Coronavirus Q&A". Bloomberg. Retrieved 18 May 2020.
  24. ^ "EUR researchers on the coronavirus | Erasmus University Rotterdam". www.eur.nl. Retrieved 19 May 2020.
  25. ^ a b c "Prof. Marion Koopmans: "We will see more of this if we topple natural balances"". European Science-Media Hub. 30 March 2020. Retrieved 18 May 2020.
  26. ^ https://www.nature.com/articles/d41586-020-03402-1
  27. ^ "Personalia | Nederlands Tijdschrift voor Geneeskunde". www.ntvg.nl. Retrieved 19 May 2020.
  28. ^ "ZIKA VIRUS AND OTHER MOSQUITO-BORNE VIRUSES" (PDF). BDEBATE. Retrieved 19 May 2020.