Marion Sims Wyeth
|John Allan Wyeth|
New York City, U.S.
|Alma mater||Princeton University
École nationale supérieure des Beaux-Arts
|Parent(s)||John Allan Wyeth
Florence Nightingale Sims
|Relatives||J. Marion Sims (maternal grandfather)
John Allan Wyeth (brother)
Wyeth was born in New York City to Florence Nightingale Sims and Dr. John Allan Wyeth, who founded the New York Polyclinic Hospital in 1882. (which became Cabrini Medical Center) His grandfather J. Marion Sims founded the first Women's Hospital in the U.S. in 1855 (it is now part of St. Lukes-Roosevelt Hospital.
Wyeth attended Princeton University and studied at the École nationale supérieure des Beaux-Arts in Paris, where he was awarded the Prix Jean LeClerc in 1913 and the Deuxième Prix Rougevin in 1914.
Wyeth worked at Carrère & Hastings. He moved to Palm Beach, Florida in 1919 where he founded the firm of Wyeth and King with his business partner Frederic Rhinelander King. He was the first Palm Beach architect to be elected a fellow of the American Institute of Architects.
Wyeth would design numerous mansions in Palm Beach during its gilded age.
- Mar-A-Lago, Palm Beach
- Norton Museum of Art, West Palm Beach
- High Point, New Jersey, Monument and associated Grey Rock Inn
- Florida Governor's Mansion
- Shangri La - Doris Duke home in Honolulu
- The Church of the Epiphany on New York City's Upper East Side 
- Wyeth, John Allan (1914). Sabre and scalpel: the autobiography of a soldier and surgeon. p. 464.
- Long Island Country Houses and Their Architects, 1860-1940 by Robert B. Mackay (Editor), Anthony K. Baker (Editor), Carol A. Traynor (Editor) - W. W. Norton & Company (February 1997) - ISBN 0-393-03856-4
- Tropical Style: Private Palm Beach by Jennifer Ash (Author), Alex McLean (Author) Abbeville Press; 2nd edition (November 1992) ISBN 1-55859-489-2
- "Epiphany history 1933-1962". Epiphanynyc.org. Retrieved 2015-08-17.
- Norval White, Elliot Willensky, Fran Leadon (2010). AIA Guide to New York City. Oxford University Press. Retrieved 2013-01-06.