Andre studied composition from 1987 to 1993 with Claude Ballif and Gérard Grisey at the Paris Conservatoire National Supérieur de Musique. In Paris, he also graduated from the École Normale Supérieure about the music of Ars subtilior (Le compossible musical de l'Ars subtilior). In 1995 he received a scholarship from the French Foreign Ministry, which enabled him to continue his studies of composition at the University of Music and Performing Arts Stuttgart with Helmut Lachenmann. In the Experimental Studio for Acoustic Art he studied electronic music with André Richard. In 1996, he was able to continue his studies in Stuttgart by a grant from the Akademie Schloss Solitude. Numerous other scholarships and residencies followed. Since then, Andre has been heard at the Donaueschingen Music Festival in 2007 with his composition ... on ... III that his large Orchester triptych ... Auf ... , and was awarded the prize of the SWR Symphony Orchestra Baden-Baden and Freiburg, since this public attention has been drawn to his work even more. But even before Andre earned numerous major awards, so at the Darmstadt Summer Courses (Kranichsteiner Music Prize 1996).
In 2002, the Ernst von Siemens Music Prize was awarded to him. Living in Berlin, Andre teaches at the Frankfurt University of Music and at the Conservatoire de Strasbourg. As part of the project "into ...", a collaboration between the Ensemble Modern and Siemens Arts Program, in cooperation with the Goethe Institute, was Andres piece "üg", jointly with the computer music and sound engineer Joachim Haas (Experimentalstudio des SWR) Others was developed in Istanbul, was premiered in October 2008 at the Alte Oper in Frankfurt by the Ensemble Modern. In 2009 he was appointed a member of the Berlin Academy of Arts and professor of composition at the Hochschule für Musik in Dresden. Since 2010 he has been a member of the Saxon Academy of Arts. 2012: Fellow of the Wissentschaftskolleg to Berlin and a member of the Bavarian Academy of Fine Arts in Munich. He lives in Berlin. On 2 March 2014 his opera "Wunderzaichen" will be premiered in Stuttgart directed by Jossi Wieler and Sergio Morabito.
Andre is well known on the continent, though does not have such a large profile in the predominantly English-speaking world. Referring to this, The Guardian noted "though Manchester festival director Alex Poots's claim that Mark Andre is "one of Europe's leading composers" is far-fetched, there is no doubt that Andre's music remains virtually unknown in the UK."
- Ein Abgrund for bass-baritone, viola and violoncello based on Georg Büchner's drama "Woyzeck" (1992)
- Un-Fini III (1993–1995) for piano
- Le loin et le profond for Ensemble (1994–1996)
- Fatal for Ensemble (1995)
- AB II for double bass clarinet, cello, cymbalon, percussion, piano and live electronics (1996/1997)
- Contrapunctus for piano (1998/1999)
- Modell for four orchestra groups (1999/2000)
- ...22,13... Musiktheater-Passion in three parts (1999–2004)
- ...als... I for bass clarinet, cello and piano (2001)
- ...als... II for double bass clarinet, cello, piano and live electronics (2001)
- ...IN... for verstärkte bass clarinet (2001)
- ...zu...' for string trio (2003/2004)
- asche for ensemble (2005)
- durch for saxophone, piano and percussion (2005/2006) - written for Trio Accanto
- ...hoc... (2006)
- ...auf... III (2007) for orchestra
- iv2 for cello solo (2007)
- iv3 for clarinet solo (2007)
- ...es... for chamber ensemble (2008)
- üg for orchestra and live electronics (2008)
- hij for orchestra (2009)
- The Guardian
- Ars musica: 20 ans d'aventures musicales - 2009 Page 162 "Du post-Boulez? La question est plutôt ailleurs: savoir comment, à partir de cette multiplicité affolante, composer son propre chemin. Certains jeunes compositeurs comme Enno Poppe ou Mark Andre apportent des solutions individuelles mais ...