The Massachusetts Mental Health Center was a historic psychiatric hospital complex at 74 Fenwood Road in the Longwood medical area of Boston, Massachusetts.
The center was founded in 1912 as the Boston Psychopathic Hospital. Its original main building and power plant were built that year, with additions in later decades including a therapeutic wing (1954) and research building (1957). The entire property was surrounded by an iron picket fence. It was listed on the National Register of Historic Places in 1994, representing one of the nation's oldest psychiatric hospitals. In 2009 the center's historic campus was acquired by Partners HealthCare and demolished the following year. The center continues to operate in modern facilities at 75 Fenwood Road.