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Mebroqualone

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Mebroqualone
Clinical data
ATC code
  • none
Legal status
Legal status
  • DE: Anlage I (Authorized scientific use only)
Identifiers
  • 3-(2-bromophenyl)-2-methylquinazolin-4(3H)-one
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H11BrN2O
Molar mass315.170 g·mol−1
3D model (JSmol)
  • BrC1=C(N2C(C3=CC=CC=C3N=C2C)=O)C=CC=C1
  • InChI=1S/C15H11BrN2O/c1-10-17-13-8-4-2-6-11(13)15(19)18(10)14-9-5-3-7-12(14)16/h2-9H,1H3 checkY
  • Key:NBUSAPJNASSKBP-UHFFFAOYSA-N checkY
  (verify)

Mebroqualone (MBQ) is a quinazolinone-class GABAergic and is an analogue of mecloqualone that has similar sedative and hypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of the GABAa receptor. It was originally synthesized in the 1960s[1] Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring. It was made illegal in Germany in 1998 but little other information is available. It would appear that this compound was sold on the black market in Germany as a designer drug analogue of mecloqualone.[2]

See also

References

  1. ^ Jackman et al. Journal of Pharmacy and Pharmacology, 1960 , vol. 12, p. 529
  2. ^ Zwölfte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften. Bundesgesetzblatt 1998: Part I Number 68, p. 3126. 7 October 1998.


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