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Mediator may refer to:

Chemistry and biology[edit]

  • Mediator (coactivator), a multiprotein complex that functions as a transcriptional coactivator
  • Endogenous mediator, proteins that enhance and activate the functions of other proteins
  • Gaseous mediator, chemicals produced by some cells that have biological signalling functions
  • Mediator or Benfluorex, a withdrawn appetite suppressant drug

Internet, software, and computer[edit]