The music video for "Medicate" was directed by Paul Minor and premiered October 2, 2009. The video is shot in black and white, with gold color effects added digitally. The video depicts the band performing the song in front of a large projection screen which shows footage of a blonde girl and of the band. During the song's bridge, singer Davey Havok kisses the girl while guitarist Jade Puget lies bleeding on the floor, his blood colored gold through the use of digital effects. This style is very similar to conception of Paco Rabanne's advertisements. Musicians look very fashionable too.