|Synonyms||MP; 6α-Methyl-17α-hydroxyprogesterone; 6α-Methyl-17α-hydroxypregn-4-en-3,20-dione|
|Chemical and physical data|
|Molar mass||344.488 g/mol|
|3D model (JSmol)|
Medroxyprogesterone (abbreviated as MP), sold under the brand name Controlestril, is a progestin which is used in veterinary medicine in France to control estrus in animals. A derivative, medroxyprogesterone acetate (MPA), is used as a medication in humans, and is far more widely known in comparison. Compared to MPA, MP is over two orders of magnitude less potent as a progestogen. MP is also notable in that it is a metabolite of MPA. Medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate, and what is almost always being referred to when the term is used is MPA and not MP.
MP, also known as 6α-methyl-17α-hydroxyprogesterone or as 6α-methyl-17α-hydroxypregn-4-en-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. It is specifically a derivative of 17α-hydroxyprogesterone with a methyl group at the C6α position. The generic name of MP is a contraction of 6α-methyl-17α-hydroxyprogesterone. It is closely related to medrogestone as well as other unesterified 17α-hydroxyprogesterone derivatives such as chlormadinone, cyproterone, and megestrol.
Society and culture
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