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Virus classification e
(unranked): Virus
Realm: Riboviria
Phylum: incertae sedis
Family: Megabirnaviridae
Genus: Megabirnavirus
Type species
  • Rosellinia necatrix megabirnavirus 1

Megabirnaviridae is a family of viruses with one genus Megabirnavirus.[1] Fungi serve as natural hosts. There is only one species in this family: the type species Rosellinia necatrix megabirnavirus 1. Diseases associated with this family include: reduced host virulence.[2][3]


Group: dsRNA



Viruses in the family Megabirnaviridae are non-enveloped, with icosahedral geometries, and T=1 symmetry. The diameter is around 50 nm. Genomes are linear and segmented, around 7kb in length. The genome codes for 4 proteins.[2][3]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Megabirnavirus Icosahedral T=1 Non-enveloped Linear Segmented

Life cycle[edit]

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by cell to cell movement. Fungi serve as the natural host. Transmission routes are parental and sexual.[2][3]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Megabirnavirus Fungi None Cytoplasmic exchange; hyphal anastomosis Cytoplasmic exchange; hyphal anastomosis Cytoplasm Cytoplasm Cytoplasmic exchange; hyphal anastomosis


  1. ^ Sato, Y; Miyazaki, N; Kanematsu, S; Xie, J; Ghabrial, SA; Hillman, BI; Suzuki, N; ICTV Report, Consortium (September 2019). "ICTV Virus Taxonomy Profile: Megabirnaviridae". The Journal of General Virology. 100 (9): 1269–1270. doi:10.1099/jgv.0.001297. PMID 31418675.
  2. ^ a b c d "ICTV Report Megabirnaviridae".
  3. ^ a b c "Viral Zone". ExPASy. Retrieved 13 August 2015.

External links[edit]