In 1950 he was amongst the founders of Eilat. Between 1952 and 1953 he was director of the Negev and Arava department of the Ministry of Development. In 1961 he became a member of the editorial board at Davar, on which he remained until 1965. In the same year he left Mapai and joined David Ben-Gurion's new Rafi party. When Ben-Gurion left Rafi to establish the National List, Avizohar followed, and was elected to the Knesset on the new party's list in the 1969 elections. On 24 April 1972 he left the National List, sitting as an Independent until joining the Alignment on 17 July 1973. He lost his seat in the 1973 elections.