Melville "Mel" Spence (2 January 1936 – 28 October 2012) was a Jamaican sprinter who competed in the 1956 Summer Olympics and in the 1964 Summer Olympics. He is the twin brother of Mal Spence, an Olympic sprint medalist.
He was a relay silver medalist at the 1955 Pan American Games and was runner-up in the individual 400 m event at the 1963 Pan American Games. He was part of the winning Jamaican 4×400 metres relay team at the 1962 Central American and Caribbean Games.
- "Melville Spence: international repute through talent and good values, says PM Simpson Miller | Government of Jamaica Office of the Prime Minister". Opm.gov.jm. 2012-11-01. Retrieved 2012-12-01.
- "Olympics". sports-reference. Retrieved 12 May 2012.
- Pan American Games. GBR Athletics. Retrieved on 2012-05-12.
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