'Melatonin Magik' is the ninth studio album by rap artist Canibus. In the years subsequent to its release the album has been universally considered to be among his finest and most cohesive work. The album contains a prolonged guest appearance by Professor Griff of Public Enemy who provides introductory or hype vocals on numerous songs. The album also features production from an impressive collective of producers such as Sicknature and ENG, as well as performance appearances by fellow rap artists such as DZK and Warbux of Warlab Records, Blaq Poet, K-Solo, and D12 among others. The song "Air Strike (Pop Killer)" generated discussion as both Canibus and DZK verbally attack Eminem in an attempt to bait him into issuing a response which never came either due to scheduling conflicts or a lack of competitive interest, and songs "Post Traumatic Warlab Stress", "Dead By Design" and "Kriminal Kindness" in particular have elicited great enthusiasm from Canibus' fans for the intellectual merits of their songwriting and respective guest appearances.
The conceptual artwork for Melatonin Magik is derived in part from the feature film The Matrix, displaying Canibus in meditative posture, unchaining himself and his listeners from structural and unknown tyrannies while alluding to the central protagonists ultimate choice of the liberating red pill as opposed to its blue counterpart. The graphic design artist credited with its illustration was requisitioned by Canibus himself through Spitboss.