Metabolic network

From Wikipedia, the free encyclopedia
Jump to: navigation, search

A metabolic network is the complete set of metabolic and physical processes that determine the physiological and biochemical properties of a cell. As such, these networks comprise the chemical reactions of metabolism, the metabolic pathways, as well as the regulatory interactions that guide these reactions.

With the sequencing of complete genomes, it is now possible to reconstruct the network of biochemical reactions in many organisms, from bacteria to human. Several of these networks are available online: Kyoto Encyclopedia of Genes and Genomes (KEGG)[1], EcoCyc [2], BioCyc [3] and metaTIGER [4]. Metabolic networks are powerful tools for studying and modelling metabolism.

Metro-style map of major metabolic pathways



The image above contains clickable links
Major metabolic pathways in metro-style map. Click any text (name of pathway or metabolites) to link to the corresponding article.
Single lines: pathways common to most lifeforms. Double lines: pathways not in humans (occurs in e.g. plants, fungi, prokaryotes). Metabolic metro orange.svg Orange nodes: carbohydrate metabolism. Metabolic metro purple.svg Violet nodes: photosynthesis. Metabolic metro red.svg Red nodes: cellular respiration. Metabolic metro pink.svg Pink nodes: cell signaling. Metabolic metro blue.svg Blue nodes: amino acid metabolism. Metabolic metro grey.svg Grey nodes: vitamin and cofactor metabolism. Metabolic metro brown.svg Brown nodes: nucleotide and protein metabolism. Metabolic metro green.svg Green nodes: lipid metabolism.

See also[edit]