Metallocarboxypeptidase D

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Metallocarboxypeptidase D
Identifiers
EC number 3.4.17.22
CAS number 153967-26-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Metallocarboxypeptidase D (EC 3.4.17.22, carboxypeptidase D (cattle, human, mouse, rat), gp180 (duck)) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Releases C-terminal Arg and Lys from polypeptides

This enzyme is activated by Co2+, and inhibited by guanidinoethylmercaptosuccinic acid.

References[edit]

  1. ^ Kuroki, K.; Eng, F.; Ishikawa, T.; Turck, C.; Harada, F.; Ganem, D. (1995). "gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family". J. Biol. Chem. 270: 15022–15028. doi:10.1074/jbc.270.25.15022. PMID 7797483. 
  2. ^ Song, L.X.; Fricker, L.D. (1995). "Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary". J. Biol. Chem. 270: 25007–25013. doi:10.1074/jbc.270.42.25007. PMID 7559630. 
  3. ^ Song, L.X.; Fricker, L.D. (1996). "Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D". J. Biol. Chem. 271: 28884–28889. doi:10.1074/jbc.271.46.28884. PMID 8910535. 

External links[edit]