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Systematic (IUPAC) name
3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpentanoic acid
CAS Registry Number 517-18-0
ATC code G03CB03
PubChem CID: 10599
ChemSpider 10154
Synonyms β-Ethyl-6-methoxy-α,α-dimethyl-2-naphthalenepropionic acid
Chemical data
Formula C18H22O3
Molecular mass 286.365 g/mol
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Methallenestril (INN) (brand names Cur-men, Ercostrol, Geklimon, Novestrine, Vallestril), also known as methallenoestril (BAN) and as methallenestrol, is a synthetic non-steroidal estrogen which was formerly used to treat menstrual issues, but is no longer marketed.[1][2][3][4] It is a seco-analogue of bisdehydrodoisynolic acid, and although methallenestril is potently estrogenic in rats, in humans it is only weakly so in comparison.[5] Vallestril was a brand of methallenestril issued by G. D. Searle & Company in the 1950s.[6]

See also[edit]


  1. ^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1295–. ISBN 978-0-412-46630-4. 
  2. ^ I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 177–. ISBN 978-94-011-4439-1. 
  3. ^ John A. Thomas; Edward J. Keenan (1986). Principles of Endocrine Pharmacology. Springer Science & Business Media. pp. 171–. ISBN 978-1-4684-5036-1. 
  4. ^ Herbai G, Ljunghall S (1983). "Normalization of hypercalcaemia of primary hyperparathyroidism by treatment with methallenestril, a synthetic oestrogen with low oestrogenicity". Urol. Int. 38 (6): 371–3. doi:10.1159/000280925. PMID 6659184. 
  5. ^ Raymond Eller Kirk; Donald Frederick Othmer (1980). Encyclopedia of chemical technology. Wiley. p. 670. ISBN 978-0-471-02065-3. 
  6. ^ Library of Congress. Copyright Office (1965). Catalog of Copyright Entries. Third Series: 1963: July-December. Copyright Office, Library of Congress. pp. 1984–.