Methotrexate-induced papular eruption

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Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities.[1]

It has been suggested that it may represent a Cutaneous small-vessel vasculitis.[2]

See also[edit]


  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 181. ISBN 0-7216-2921-0.
  2. ^ Mebazaa A, Kenani N, Denguezli M, et al. (January 2008). "Methotrexate-induced papular eruption following treatment of psoriasis". Ann Pharmacother. 42 (1): 138–41. PMID 18094347. doi:10.1345/aph.1K271.