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Legal status
Legal status
  • 2-(3-Methoxyphenyl)-2-(propylamino)cyclohexanone
CAS Number
PubChem CID
Chemical and physical data
Molar mass261.365 g·mol−1
3D model (JSmol)
  • COc1cccc(c1)C2(NCCC)CCCCC2=O
  • InChI=1S/C16H23NO2/c1-3-11-17-16(10-5-4-9-15(16)18)13-7-6-8-14(12-13)19-2/h6-8,12,17H,3-5,9-11H2,1-2H3

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist[1] that is closely related to substances such as methoxetamine and PCPr.[2] It has been sold online as a designer drug, first being identified in Denmark in October 2019,[3] and is illegal in Finland.[4]

See also[edit]


  1. ^ Irie T, Yamazaki D, Kikura-Hanajiri R (July 2021). "A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice". Forensic Toxicology. 39 (2): 474–80. doi:10.1007/s11419-021-00571-0. S2CID 232273277.
  2. ^ Goncalves, R.; Castaing, N.; Richeval, C.; Ducint, D.; Titier, K.; Morvan, E.; Grélard, A.; Loquet, A.; Molimard, M. (April 2022). "Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat". Forensic Science International. 333: 111215. doi:10.1016/j.forsciint.2022.111215. ISSN 0379-0738. PMID 35151938. S2CID 246685658.
  3. ^ "EU Early Warning System Situation Report. Situation report 1" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). June 2020.
  4. ^ Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista