Metomidate

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Metomidate
Metomidate.svg
Clinical data
ATCvet code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.023.971
Chemical and physical data
Formula C13H14N2O2
Molar mass 230.263 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965[1] and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.[2]

11C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.[3][4]

See also[edit]

References[edit]

  1. ^ BE Patent 662474
  2. ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 683. ISBN 978-3-88763-075-1. Retrieved 27 October 2011. 
  3. ^ Khan TS; Sundin A; Juhlin C; Långström B; et al. (2003). "11C-metomidate PET imaging of adrenocortical cancer". European Journal of Nuclear Medicine and Molecular Imaging. 30 (3): 403–410. doi:10.1007/s00259-002-1025-9. PMID 12634969. 
  4. ^ Minn H; Salonen A; Friberg J; Roivainen A; et al. (June 2004). "Imaging of adrenal incidentalomas with PET using (11)C-metomidate and (18)F-FDG". J. Nucl. Med. 45 (6): 972–9. PMID 15181132.