The Hurricanes and Hokies first met on November 13, 1953 in Miami. Miami and Virginia Tech have met in two bowl games, the 1966 Liberty Bowl and 1981 Peach Bowl. The two teams have played annually since 1992, and the rivalry developed when the Hokies became a member of the Big East Conference for football in 1991. When the Atlantic Coast Conference (ACC) expanded in 2004, both Miami and Virginia Tech became members of the ACC. Both teams continue to compete annually as part of the ACC's Coastal Division.
The series was one-sided until 1995 when Virginia Tech took their first game against Miami in Blacksburg. Beginning in that year, the series has been in favor of Virginia Tech, 14–8. There have been several notable games in this time, including 11 meetings in which both teams were ranked in the top 25 and four meetings where both teams were in the top 10. In 2000, #2 Virginia Tech lost to #3 Miami at the Orange Bowl 41–21. In 2003, #2 Miami had a regular season winning streak snapped by the Hokies in Lane Stadium. In 2004, the first year for both schools in the ACC, both teams met in Miami at the Orange Bowl stadium for the final game of the regular season, which became a de facto ACC Championship Game, with the winner getting a berth in a Bowl Championship Series bowl game. #10 Virginia Tech beat #9 Miami 16–10. In 2005, #5 Miami beat #3 Virginia Tech in Blacksburg 27–7.