Michael Christopher Wendl

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Michael Wendl
Nationality Flag of the United States.svg American
Fields Computational biology
Doctoral advisor Ramesh K. Agarwal
Known for Phred base calling
Couette flow
DNA sequencing theory

Michael Christopher Wendl is a mathematician and biomedical engineer who developed much of DNA sequencing theory[1] and co-wrote Phred,[2] a widely used DNA trace analyzer.[3][4] His result for the multiple-group birthday proposition[5] solves various "collision problems", including overlap quantification in DNA fragment mapping and some types of P2P searching.[6] He obtained the general solution of the Couette problem,[7] for which only various idealized results had existed previously.[8]

Wendl is of ethnic German heritage and is the son of the aerospace engineer Michael J. Wendl.[9]


  1. ^ Dorman, N (2006) The long and short of it, BioTechniques 41(4), pp 367.
  2. ^ Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Research 8(3), 175–185. PMID 9521921 full article
  3. ^ Koboldt, D. C. and Miller, R. D. (2011) Identification of Polymorphic Markers for Genetic Mapping, chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.
  4. ^ Highsmith, W. E. (2006) Electrophoretic Methods for Mutation Detection and DNA Sequencing, chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press
  5. ^ Wendl MC (2003) Collision probability between sets of random variables, Stat. Prob. Lett. 64(3), 249–254.
  6. ^ Hautakorpi, J and Schultz, G (2010) A Feasibility Study of an Arbitrary Search in Structured Peer-to-Peer Networks, IEEE Computer Communications and Networks, Proc ICCCN, pp 1–8.
  7. ^ Wendl MC (1999) General Solution for the Couette Flow Profile, Physical Review E 60(5), 6192–6194.
  8. ^ Bordag LA et al. (2005) Interaction of a rotational motion and an axial flow in small geometries for a Taylor–Couette problem , J. Fluids and Structures 20(5), 621–641.
  9. ^ P Hummel and N Fuhry: "Sackelhausen im Banat" Volume 3, published by Heimatsortsgemeinschaft Sackelhausen, Reutlingen FRG, 2007, pages 2236-2237.

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