Michael Christopher Wendl

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Michael Wendl
Nationality American
Fields Computational biology
Doctoral advisor Ramesh K. Agarwal
Known for Phred base calling
Couette flow
DNA sequencing theory

Michael Christopher Wendl is a mathematician and biomedical engineer who developed much of DNA sequencing theory[1] and co-wrote Phred,[2] a widely used DNA trace analyzer.[3][4] His result for the multiple-group birthday proposition[5] solves various "collision problems", including overlap quantification in DNA fragment mapping and some types of P2P searching.[6] He obtained the general solution of the Couette problem,[7] for which only various idealized results had existed previously.[8] Wendl is of ethnic German heritage and is the son of the aerospace engineer Michael J. Wendl.[9]


  1. ^ Dorman, N (2006) The long and short of it, BioTechniques 41(4), pp 367.
  2. ^ Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Research 8(3), 175–185. PMID 9521921 full article
  3. ^ Koboldt, D. C. and Miller, R. D. (2011) Identification of Polymorphic Markers for Genetic Mapping, chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.
  4. ^ Highsmith, W. E. (2006) Electrophoretic Methods for Mutation Detection and DNA Sequencing, chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press
  5. ^ Wendl MC (2003) Collision probability between sets of random variables, Stat. Prob. Lett. 64(3), 249–254.
  6. ^ Hautakorpi, J and Schultz, G (2010) A Feasibility Study of an Arbitrary Search in Structured Peer-to-Peer Networks, IEEE Computer Communications and Networks, Proc ICCCN, pp 1–8.
  7. ^ Wendl MC (1999) General Solution for the Couette Flow Profile, Physical Review E 60(5), 6192–6194.
  8. ^ Bordag LA et al. (2005) Interaction of a rotational motion and an axial flow in small geometries for a Taylor–Couette problem , J. Fluids and Structures 20(5), 621–641.
  9. ^ P Hummel and N Fuhry: "Sackelhausen im Banat" Volume 3, published by Heimatsortsgemeinschaft Sackelhausen, Reutlingen FRG, 2007, pages 2236-2237.

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