Michael Cuffe (1694 - 24 July 1744) was an Irish Member of Parliament.
He was the son of Francis Cuffe by his wife Honora, daughter of Archbishop Michael Boyle. His paternal grandmother was the sister of Francis Aungier, 1st Earl of Longford.
He was elected to the Irish House of Commons for County Mayo in 1719 - he resided at Ballinrobe - and then for Longford Borough in November 1727, sitting until his death.
His daughter Elizabeth married Thomas Pakenham in 1739. Pakenham was created Baron Longford in 1756 and she was created Countess of Longford in 1785.