Michael N. Hall

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Michael N. Hall
Michael N Hall 2014.jpg
Michael N. Hall (2014)
NationalitySwiss, American
Alma materUniversity of North Carolina at Chapel Hill (B.S., 1976)
Harvard University (Ph.D., 1981)
Known formTOR
AwardsLouis-Jeantet Prize for Medicine (2009) [1]
Marcel Benoist Prize (2012)
Lasker Prize (2017)
Scientific career
FieldsMolecular biology
InstitutionsUniversity of North Carolina at Chapel Hill
Harvard University
Institut Pasteur
University of California, San Francisco
Biozentrum University of Basel

Michael Nip Hall is an American and Swiss molecular biologist and Professor at the Biozentrum University of Basel, Switzerland.

Life[edit]

Hall grew up in South America (Venezuela, Peru). He earned a Bachelor of Science in Zoology from the University of North Carolina at Chapel Hill in 1976, and a PhD in Molecular Genetics from Harvard University in 1981. Hall was a postdoctoral fellow at the Institut Pasteur in Paris and at the University of California, San Francisco. He was appointed an Assistant Professor at the Biozentrum of the University of Basel in 1987, and became a Full Professor in 1992. From 1995 to 1998 and from 2002 to 2009 he was head of the Division of Biochemistry, and from 2002 until 2009 was Deputy Director of the Biozentrum.[2]

Work[edit]

Hall is a pioneer in the fields of TOR signaling and cell growth control.[3] In 1991, Michael N. Hall discovered a protein, which regulates cell growth, cell size and cell division in yeast cells.[4] Since the function of this protein is inhibited by the substance rapamycin, Hall gave the growth regulator the name «Target of Rapamycin» or for short «TOR». TOR is a conserved protein kinase activated by growth factors, nutrients, and insulin. It is a central controller of cell growth and metabolism. TOR plays a key role in aging and the development of diseases such as cancer, obesity, Diabetes mellitus, and cardiovascular disease. Insights into TOR signaling pathways have been applied for new therapeutic strategies. [5][6] Hall received the 2017 Albert Lasker Basic Medical Research Award.[7]

Awards and honors[edit]

References[edit]

  1. ^ Louis-Jeantet Prize
  2. ^ Curriculum Vitae Biozentrum.unibas.ch Retrieved 2013-10-22
  3. ^ Short Biography Archived 2014-10-18 at the Wayback Machine., De Duve Institute Retrieved 2013-10-22
  4. ^ "Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast". Science. 253: 905–9. Aug 1991. doi:10.1126/science.1715094. PMID 1715094.
  5. ^ Introduction Michael N. Hall Archived 2014-10-16 at the Wayback Machine. bioss.uni-freiburg.de Retrieved 2013-10-22
  6. ^ Unveiling the Secret of Cell Growth Karger.com Retrieved 2015-09-16
  7. ^ Foundation, Lasker. "Nutrient-activated TOR proteins that regulate cell growth | The Lasker Foundation". The Lasker Foundation. Retrieved 2018-03-05.
  8. ^ European Molecular Biology Organization Membership Guide 2012 Retrieved 2013-10-22
  9. ^ Cloëtta Prize Website Retrieved 2013-10-22
  10. ^ Louis-Jeantet Prize
  11. ^ Marcel Benoist Prize 2012 marcel-benoist.ch Retrieved 2013-10-22
  12. ^ SAMS-Member samw.ch Retrieved 2013-10-22
  13. ^ Sir Hans Krebs Lecture Archived 2014-01-16 at the Wayback Machine. FEBS-EMBO 2014 Retrieved 2013-10-22
  14. ^ First Breakthrough Prize in Life Sciences awarded to Swiss scientist. In: University of Basel, December 13, 2013
  15. ^ "Laureates: 2014". Breakthrough Prize in Life Sciences, Retrieved 2014-02-05.
  16. ^ "ERC Synergy Grant: EUR 11 million for Cancer Research" In: University of Basel, December 18, 2013
  17. ^ National Academy of Sciences Members and Foreign Associates Elected. Archived 2015-08-18 at the Wayback Machine. nasonline.org Retrieved 2014-06-24
  18. ^ Michael N. Hall: Recipient of the Canada Gairdner International Award, 2015; Gairdner Foundation (gairdner.org); Retrieved 2015-03-31
  19. ^ Debrecen Award for Molecular Medicine 2016; University of Debrecen (unideb.hu); Retrieved 2017-05-23
  20. ^ Doctor honoris causa, University of Geneva 2016; University of Geneva (unige.ch); Retrieved 2017-05-23
  21. ^ Szent-Györgyi Prize 2017; National Foundation for Cancer (nfcr.org); Retrieved 2017-05-23
  22. ^ http://www.laskerfoundation.org/awards/year/2017/

External links[edit]