Michael Neuberger

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Michael Neuberger
Michael Samuel Neuberger

(1953-11-02)2 November 1953[1]
London, United Kingdom
Died26 October 2013(2013-10-26) (aged 59)
Cambridge, United Kingdom
Alma mater
Scientific career
InstitutionsLaboratory of Molecular Biology
ThesisTransducing phages for analysis of gene duplications (1978)
Doctoral advisorBrian S. Hartley

Michael Samuel Neuberger FRS FMedSci (2 November 1953 – 26 October 2013) was a British biochemist and immunologist.[3][4][5][6]


Born in London, he was educated at Westminster School, and then read Natural Sciences at Trinity College, Cambridge as a scholar where he obtained a Master of Arts; he then obtained a PhD at Imperial College, London.[7][8]


He was a fellow of, and director of studies at Trinity College, Cambridge from 1985[9] and Professor of molecular immunology there since 2002. He supervised students reading the Natural Sciences Tripos in the fields of cell biology and biochemistry.

He was also joint head of the Protein and Nucleic Acid Chemistry division at the Medical Research Council's Laboratory of Molecular Biology in Cambridge, UK,[10] alongside Mariann Bienz.[11]

He is most notable for discovering the mechanism of somatic hypermutation.

Awards and honours[edit]

He was elected a Fellow of the Royal Society (FRS) in 1993[2] and was awarded their GlaxoSmithKline Prize in 2003. He also received the Novartis medal in 2002 and delivered the Novartis medal lecture, entitled "Antibodies: a Paradigm for the Evolution of Molecular Recognition" on 9 April 2002 at Heriot-Watt University, Edinburgh.

Personal life[edit]

He was the son of Albert Neuberger, the brother of David Neuberger, James Neuberger, and Anthony Neuberger, and the brother-in-law of Julia Neuberger. He died of myeloma, a cancer of antibody-producing cells, at Addenbrooke's Hospital, Cambridge, on 26 October 2013.


  1. ^ "Prof Michael Neuberger, FRS Authorised Biography". Debretts.com. Retrieved 2 December 2013.
  2. ^ a b "Fellowship of the Royal Society 1660–2015". London: Royal Society. Archived from the original on 15 July 2015.
  3. ^ Cattaneo, A.; Sitia, R. (2013). "Remembering Michael S Neuberger (1953-2013)". The EMBO Journal. 32 (24): 3112–3113. doi:10.1038/emboj.2013.251. PMC 3981150.
  4. ^ "Michael_Neuberger Obituary". Medical Research Council. Archived from the original on 8 December 2015.
  5. ^ Rajewsky, K. (2014). "Michael S. Neuberger 1953–2013". Proceedings of the National Academy of Sciences. 111 (8): 2862–2863. doi:10.1073/pnas.1401334111. ISSN 0027-8424. PMC 3939883. PMID 24532658.
  6. ^ Gearhart, Patricia J.; Kelsoe, Garnett (2014). "A tribute to Michael S. Neuberger". Journal of Clinical Investigation. 124 (1): 3–5. doi:10.1172/JCI74366. ISSN 0021-9738. PMC 3871264. PMID 24382382. open access
  7. ^ Neuberger, Michael Samuel (1978). Transducing phages for analysis of gene duplications (PhD thesis). University of London. OCLC 500526968.
  8. ^ KJ Patel. "Michael Neuberger obituary". The Guardian. Retrieved 2 December 2013.
  9. ^ "Trinity College directory of Fellows". Retrieved 22 December 2010.
  10. ^ Jones, P. T.; Dear, P. H.; Foote, J.; Neuberger, M. S.; Winter, G. (1986). "Replacing the complementarity-determining regions in a human antibody with those from a mouse". Nature. 321 (6069): 522–525. doi:10.1038/321522a0. PMID 3713831.
  11. ^ "Protein and Nucleic Acid Chemistry Division". MRC Laboratory of Molecular Biology. 17 October 2013. Retrieved 2 December 2013.