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Oto was born in Japan. He received a bachelor’s degree in biochemistry from Chiba University in 1980 and a Ph.D. from the School of Medicine at Tokyo Medical and Dental University. He is the department director of biotechnology at Tokyo Technical College and a visiting Lecturer at Tokyo University of Agriculture and Technology, Maebashi Institute of Technology and Kogakuin University.
- Oto, M; Miyake, S; Yuasa, Y (2013-03-25). "Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus". Anal. Biochem. 213: 19–22. PMID 8238876. doi:10.1006/abio.1993.1379.
- Oto, M (2013-03-25). "Identification of Mutated p53 in Cancers by Nongel-Sieving Capillary Electrophoretic SSCP Analysis". Methods Mol Med. 27: 127–38. PMID 21374295. doi:10.1385/1-59259-689-4:127.
- Tomita, N; Oto, M (2013-03-25). "Molecular genetic diagnosis of familial tumors". Int J Clin Oncol. 9: 246–56. PMID 15375700. doi:10.1007/s10147-004-0421-5.