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Mid-fusiform sulcus

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Mid-fusiform sulcus
Latinsulcus sagittalis gyri fusiformis
Anatomical terms of neuroanatomy

The mid-fusiform sulcus is a shallow sulcus that divides the fusiform gyrus into lateral and medial partitions.[1][2] Functionally, the MFS divides both large-scale functional maps and identifies fine-scale functional regions such as the anterior portion of the fusiform face area.[3]



Cytoarchitectonically, the lateral and medial sides of the MFS are dissociable.[1] The anterior and posterior portion of the MFS also have different long-range connections. The vertical occipital fasciculus terminates in the posterior aspects of the MFS, while the arcuate fasciculus terminates in the anterior portions of the MFS.[4]



The mid-fusiform sulcus was first identified in 1896 by Gustav Retzius. Retzius is known for many other discoveries such as Cajal–Retzius cells. He first identified the MFS as the sulcus sagittalis gyri fusiformis. Since his label, there have been several other proposed labels, but the MFS nomenclature is the most widely accepted in present day.[2]


  1. ^ a b Weiner, K. S.; et al. (2013). "The mid-fusiform sulcus: A landmark identifying both cyotarchitectonic and functional divisions of human ventral temporal cortex". NeuroImage. 84: 453–465. doi:10.1016/j.neuroimage.2013.08.068. PMC 3962787. PMID 24021838.
  2. ^ a b Weiner, K. S.; et al. (2015). "The anatomical and functional specialization of the fusiform gyrus". Neuropsychologia. 83: 48–62. doi:10.1016/j.neuropsychologia.2015.06.033. PMC 4714959. PMID 26119921.
  3. ^ Grill-Spector, Kalanit; Weiner, Kevin S. (2014). "The functional architecture of the ventral temporal cortex and its role in categorization". Nature Reviews Neuroscience. 15 (8): 536–548. doi:10.1038/nrn3747. PMC 4143420. PMID 24962370.
  4. ^ Yeatman, J. D.; et al. (2014). "The vertical occipital fasciculus: a century of controversy resolved by in vivo measurements". Proceedings of the National Academy of Sciences. 111 (48): E5214–E5223. doi:10.1073/pnas.1418503111. PMC 4260539. PMID 25404310.