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Midol is a brand of over-the-counter analgesic drugs marketed for menstrual cramping and other effects related to premenstrual syndrome and menstruation. Various subbrands are formulated using different active ingredients. Midol is distributed by Bayer.

Midol was originally sold in 1911 as a headache and toothache remedy that was considered safer because it did not use the narcotics typically used at the time.[1] It was then promoted as a cure for hiccups claiming it controlled spasms, and finally as a remedy for menstrual cramps and bloating.[2][3][4][5] A formulation sold in the 1980s was made with the sympathomimetic cinnamedrine.[6] It had been reported to have abuse potential as an appetite suppressant and sympathomimetic agent.

The "Midol Complete" formulation consists of:

The "Extended Relief" formulation consists of:

The "Teen" formulation consists of:

The "Liquid Gels" formulation consists of:

The "PM" formulation consists of:

There are concerns drugs like Midol, which is a NSAID, increases risk of bleeding, kidney damage and has other negative effects on cardiovascular system. [7]


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