Born in Clear Lake, Iowa, Knutson moved to La Crosse, Wisconsin, where he became the news director for WKTY. From 1955 until 1965, Knutson was the Mayor of La Crosse. Knutson served in the Wisconsin State Senate from 1969 until 1977 retiring because of health reasons.
- 'Ex-mayor Knutson dies at 63,' Doug Rainey, La Crosse Tribune, March 23, 1981. The La Crosse Tribune article has Knutson as being born in 1917 as does the Social Security death registry and Oak Grove Cemetery in La Crosse. Knutson's entry in the Wisconsin Blue Book and Politicalgraveyard.com has Knutson being born in 1918.
- 'Milo Knutson To End State Senate Career,' La Crosse Tribune, January 23, 1976
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