Milosh started learning classical cello at age three, took up drumming, and studied jazz and vocals at university.
The Los Angeles-based record label Plug Research released two of Milosh's albums including 2004's You Make Me Feel and 2006's Meme. In 2008, he contributed the track "Then It Happened" on the Ghostly International/Williams Street album Ghostly Swim, which was released as a free digital download. Later that year he released his third record, iii, with Plug Research in the U.S. and Studio !K7 in the EU. In 2009 he collaborated with Paul Pfisterer on album New Territory. He formed the band Rhye, with Robin Hannibal, and they released the debut album, Woman in March 2013. He released his 4th solo record, Jetlag, in November 2013 on his own label, Deadly. In July 2017 Rhye released a single entitled 'Please', and - through social media - promised the release of a second album later that year. In February 2018, Rhye released a follow-up album to Woman entitled Blood.